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Effectiveness of Tralokinumab in Different Phenotypes of Atopic Dermatitis: A Real-World Study.
Dermatol Ther (Heidelb)
January 2025
Department of Medical-Surgical Sciences and Biotechnologies, Dermatology Unit "Daniele Innocenzi", "Sapienza" University of Rome, Polo Pontino, 04100, Latina, Italy.
Introduction: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by pruritus and a relapsing course, affecting approximately 25% of children and 4-7% of adults. This study evaluated the efficacy, safety, and quality-of-life impact of tralokinumab, a humanized monoclonal antibody targeting interleukin-13 (IL-13), in treating moderate-to-severe AD in a real-world setting, with a focus on different AD phenotypes.
Methods: An observational cohort of 30 adults treated with tralokinumab for ≥ 16 weeks was analyzed.
Physical-Chemical Characterization of Fruit Harvested at Different Maturity Stages of Grafted Yellow Pitahaya ( Haw.).
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January 2025
Tumbaco Experimental Farm, Santa Catalina Research Site, National Institute of Agricultural Research (INIAP), Tumbaco 170902, Ecuador.
The physicochemical properties of fruits at different maturity stages using grafting technology are of great importance since grafting can alter the nutritional and functional parameters of the fruit. In this study, grafted yellow pitahaya ( Haw.) fruit, grown on live tutors, was evaluated from stages 0 to 5.
View Article and Find Full Text PDFHeartwood/Sapwood Characteristics of Oliv. Trunks and Their Relationship with Soil Physicochemical Properties in the Lower Tarim River, Northwest China.
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January 2025
College of Ecology and Environment, Xinjiang University, Urumqi 830046, China.
The characteristics of heartwood and sapwood not only reflect tree growth and site quality but also provide insights into habitat changes. This study examines the natural Oliv. forest in the Arghan section of the lower Tarim River, comparing the heartwood and sapwood characteristics of at different distances from the river, as well as at varying trunk heights and diameters at breast height (DBH).
View Article and Find Full Text PDFRelatedness of White-Tailed Deer from Culling Efforts Within Chronic Wasting Disease Management Zones in Minnesota.
Pathogens
January 2025
U.S. Geological Survey, Pennsylvania Cooperative Fish and Wildlife Research Unit, 403 Forest Resources Building, The Pennsylvania State University, University Park, PA 16802, USA.
In white-tailed deer (), closely related females form social groups, avoiding other social groups. Consequently, females infected with chronic wasting disease (CWD) are more likely to infect social group members. Culling has been used to reduce CWD transmission in high-risk areas; however, its effectiveness in removing related individuals has not been assessed.
View Article and Find Full Text PDFAnatomical Adaptations of Halophyte Leaves ( [Forsskal] Asch. and L.) in Response to Cement Dust Pollution in Arid Environments.
Life (Basel)
January 2025
Biology Department, College of Science, King Khalid University [KKU], Abha 61413, Saudi Arabia.
This study investigates the anatomical adaptations of leaves from two halophyte species, (Forsskal) Asch. and L., in response to pollutants from a cement factory and human activities.
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