Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1001/jama.2024.27251 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Occurrence and molecular characterization of Cryptosporidium oocysts in chickens from Egypt, and a meta-analysis for Cryptosporidium infections in chickens worldwide.
Vet Parasitol Reg Stud Reports
January 2025
Parasitology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address:
Cryptosporidium is a leading cause of diarrhea in children and immunocompromised patients. Various animals and birds can also be infected with this protist, and Cryptosporidium zoonosis is common. A few reports have been published worldwide on Cryptosporidium infections in chickens.
View Article and Find Full Text PDFPatients Are Flocking to Compounded Weight-Loss Drugs, but Are They Safe?
JAMA
January 2025
Freelance Journalist, Boulder, Colorado.
Advancements in textile techniques for cardiovascular tissue replacement and repair.
APL Bioeng
December 2024
Innovative Global Program College of Engineering, Shibaura Institute of Technology, Saitama, Japan.
In cardiovascular therapeutics, procedures such as heart transplants and coronary artery bypass graft are pivotal. However, an acute shortage of organ donors increases waiting times of patients, which is reflected in negative effects on the outcome for the patient. Post-procedural complications such as thrombotic events and atherosclerotic developments may also have grave clinical implications.
View Article and Find Full Text PDFRestoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer.
bioRxiv
August 2024
Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
Article Synopsis
- * A comparison of non-cancerous and patient-derived VFC cells shows an association between cancer progression, reduction in specific cell adhesion proteins, and changes in how cells move collectively.
- * Mimicking the normal mechanical activity of healthy tissue can reduce tumor-promoting factors, while a correlation was found between ECM content, a signaling protein (YAP), and patient survival, suggesting potential therapeutic strategies targeting these pathways.
Development of Biolayer Interferometry (BLI)-Based Double-Stranded RNA Detection Method with Application in mRNA-Based Therapeutics and Vaccines.
Pharmaceutics
September 2024
Protein Biochemistry, Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA.
Article Synopsis
- IVT mRNA is promising for therapies and vaccines, but double-stranded RNA (dsRNA) impurities can trigger unwanted immune responses and negative patient effects.
- Current detection methods for dsRNA, like gel electrophoresis and ELISA, are often either slow or lack sensitivity, especially for modified uridines.
- This study presents a new biolayer interferometry (BLI) assay using Flock House Virus B2 protein that effectively detects various forms of dsRNA with modifications, improving sensitivity and enabling real-time monitoring during mRNA production to reduce immunogenicity risks.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!