Corrected Axial Length and Choroidal Thickness: A Correlation Analysis for Scientific Purposes.

J Pers Med

Eye Unit-Department of Medicine, Surgery, Dentistry "Scuola Medica Salernitana", University of Salerno, via S. Allende, 84081 Baronissi, Italy.

Published: January 2025

Choroidal thickness (ChT) is an important measurement for evaluating eye and systemic disorders, but it is influenced by numerous elements, especially axial length (AL). It is known that the presence of a linear relationship between ChT and AL exists, but recently it has been shown that the AL measurement obtained with the current optical biometry is not very precise and needs to be corrected. This study aimed to verify if a similar correlation also persists with this corrected AL (ALc). All subjects underwent a complete eye examination, including spectral domain optical coherence tomography (OCT) with enhanced depth image (EDI) mode and AL measurement with IOLMaster. After a normality check of the data, the correlations between ChT with AL and ALc were investigated through the Pearson correlation coefficient. values < 0.05 were considered statistically significant. In total, 100 eyes of 50 healthy patients were evaluated. The mean AL was 24.36 ± 1.23 mm and mean ALc was 24.25 ± 1.22 mm. The mean nasal ChT, subfoveal ChT, and temporal ChT were, respectively, 250.57 ± 93.93 µm, 307.18 ± 101.66 µm, and 313.72 ± 88.86 µm. A significant negative linear correlation was found by comparing both AL and ALc to ChT (all r < -0.500, all < 0.050). The negative linear correlation was stronger between nasal ChT and both AL and ALc (all r = -0.581). Through OCT and optical biometry, we confirmed that a statistically significant correlation persists between ALc and ChT, equal to the uncorrected AL. On these bases, in ChT studies or protocols, we recommend stratifying population according to ALc because linear correlation is still present; however, the cut-off values should be changed according to the systematic errors in optical biometry. In addition, both AL and ChT changes should be evaluated according to ALc.

Download full-text PDF

Source
http://dx.doi.org/10.3390/jpm15010015DOI Listing

Publication Analysis

Top Keywords

optical biometry
12
linear correlation
12
cht
11
axial length
8
choroidal thickness
8
correlation persists
8
alc
8
cht alc
8
nasal cht
8
negative linear
8

Similar Publications

A Review on Face Mask Recognition.

Sensors (Basel)

January 2025

School of Information and Communications Engineering, Xi'an Jiaotong University, Xi'an 710049, China.

This review offers a comprehensive and in-depth analysis of face mask detection and recognition technologies, emphasizing their critical role in both public health and technological advancements. Existing detection methods are systematically categorized into three primary classes: feaRture-extraction-and-classification-based approaches, object-detection-models-based methods and multi-sensor-fusion-based methods. Through a detailed comparison, their respective workflows, strengths, limitations, and applicability across different contexts are examined.

View Article and Find Full Text PDF

Interdisciplinary examination of test materials requires careful consideration of how forensic routines can influence each other. This influence can be direct and obvious, or indirect and subtle. A multidisciplinary collaborative exercise (MdCE) should test a forensic laboratory's ability to account for these difficulties.

View Article and Find Full Text PDF

To investigate the pattern and threshold of physiological growth, defining as axial length (AL) elongation that results in little refraction progression, among Chinese children and teenagers, a total of 916 children aged between 7 and 18 years from a 6-year longitudinal cohort study were included for analysis. Ocular biometry, cycloplegic refraction and demographic data were obtained annually. Physiological growth was calculated based on myopic progression and Gullstrand eye model, respectively.

View Article and Find Full Text PDF

Intraocular lens power calculation in cataract patients with keratoconus: Bayesian network meta-analysis.

Int Ophthalmol

January 2025

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, No.1, Dong Jiao Min Xiang, Dong Cheng District, Beijing, 100730, China.

Purpose: To compare the accuracy of intraocular lens (IOL) power calculation formulas in cataract patients with keratoconus (KC).

Methods: This study followed the Preferred Reporting Items for Systematic Reviews and Meta-analysis statementand and was registered on PROSPERO (CRD42024568997). Pubmed, Web of Science, Cochrane Library, and EMBASE were searched for retrospective and prospective clinical studies published until October 2024.

View Article and Find Full Text PDF

Purpose: To comprehensively evaluate the tilt of the crystalline lens in phakic eyes and its relationship with optical biometry parameters.

Setting: The retrospective analysis was conducted at the Department for Ophthalmology and Optometry, Kepler University Clinic in Linz, Austria.

Design: Lens tilt assessment was performed through a combined analysis of optical biometry (IOL Master 700) and anterior segment optical coherence tomography (AS-OCT) data to understand its relationship.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!