Optical Coherence Tomography (OCT) is a crucial imaging modality for diagnosing and monitoring retinal diseases. However, the accurate segmentation of fluid regions and lesions remains challenging due to noise, low contrast, and blurred edges in OCT images. Although feature modeling with wide or global receptive fields offers a feasible solution, it typically leads to significant computational overhead. To address these challenges, we propose LKMU-Lite, a lightweight U-shaped segmentation method tailored for retinal fluid segmentation. LKMU-Lite integrates a Decoupled Large Kernel Attention (DLKA) module that captures both local patterns and long-range dependencies, thereby enhancing feature representation. Additionally, it incorporates a Multi-scale Group Perception (MSGP) module that employs Dilated Convolutions with varying receptive field scales to effectively predict lesions of different shapes and sizes. Furthermore, a novel Aggregating-Shift decoder is proposed, reducing model complexity while preserving feature integrity. With only 1.02 million parameters and a computational complexity of 3.82 G FLOPs, LKMU-Lite achieves state-of-the-art performance across multiple metrics on the ICF and RETOUCH datasets, demonstrating both its efficiency and generalizability compared to existing methods.
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http://dx.doi.org/10.3390/e27010060 | DOI Listing |
Diagnostics (Basel)
January 2025
Department of Ophthalmology Antalya Training and Research Hospital, Varlık, Kazım Karabekir Cd., 07100 Antalya, Turkey.
This study aims to evaluate the quantitative changes in retinal nerve fiber layer (RNFL) thickness and radial peripapillary capillary (RPC) vessel density in patients with chronic central serous chorioretinopathy (CSCR), specifically excluding the peripapillary region. A prospective case-control study was conducted at the Antalya Training and Research Hospital, Health Sciences University, involving 65 patients with chronic CSCR. Participants were categorized into two groups based on the presence or regression of subretinal fluid (SRF).
View Article and Find Full Text PDFDiagnostics (Basel)
January 2025
Department of Ophthalmology, Policlinico Riuniti Foggia, University of Foggia, 71122 Foggia, Italy.
: In this study, we evaluated the incidence of cystoid macular edema (CME) after pars plana vitrectomy (PPV) for different retinal pathologies and assessed the role of optical coherence tomography (OCT) biomarkers in guiding treatment decisions in post-surgical CME patients who were refractory to medical therapy over a follow-up period of 12 months. : Medical records of consecutive pseudophakic patients, who underwent PPV for different retinal pathologies, were retrospectively evaluated in this single-center, uncontrolled study. The incidence of post-PPV CME was assessed.
View Article and Find Full Text PDFCurr Eye Res
January 2025
Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA.
Purpose: This study aims to conduct a mini review of published literature concerning the role of exosomes in the field of ophthalmology, with a specific focus on Age-Related Macular Degeneration (AMD).
Methods: In this study, a comprehensive search was conducted using PubMed and Google Scholar to identify relevant publications. Additionally, trials submitted to clinicaltrials.
Ophthalmologie
January 2025
Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Deutschland.
The accurate diagnosis of central serous chorioretinopathy (CSC) and its distinction from differential diagnoses is crucial for effective patient counseling and treatment. This is achieved through a targeted patient history and multimodal imaging, which distinguish CSC from other ocular diseases also characterized by subretinal fluid and changes in the retinal pigment epithelium. In this article we identify the key differential diagnoses of CSC and illustrate the characteristic differential diagnostic features of each disease.
View Article and Find Full Text PDFEntropy (Basel)
January 2025
School of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing 100081, China.
Optical Coherence Tomography (OCT) is a crucial imaging modality for diagnosing and monitoring retinal diseases. However, the accurate segmentation of fluid regions and lesions remains challenging due to noise, low contrast, and blurred edges in OCT images. Although feature modeling with wide or global receptive fields offers a feasible solution, it typically leads to significant computational overhead.
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