Revealing interactions in complex systems from observed collective dynamics constitutes a fundamental inverse problem in science. Some methods may reveal undirected network topology, e.g., using node-node correlation. Yet, the direction of the interaction, thus a causal inference, remains to be determined - especially in steady-state observations. We introduce a method to infer the directionality within this network only from a "snapshot" of the abundances of the relevant molecules. We examine the validity of the approach for different properties of the system and the data recorded, such as the molecule's level variability, the effect of sampling and measurement errors. Simulations suggest that the given approach successfully infer the reaction rates in various cases.
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http://dx.doi.org/10.1038/s41598-025-86332-0 | DOI Listing |
J Health Organ Manag
January 2025
Amrita School of Business - Amritapuri Kollam Campus, Kollam, India.
Purpose: This paper aims to delve into the critical aspect of supplier selection in the healthcare sector, emphasizing the significance of strategic sourcing in enhancing operational efficiency and quality of services. The primary aim is to develop a comprehensive framework for supplier evaluation that aligns with the unique requirements of hospitals, ultimately improving procurement processes and patient care outcomes.
Design/methodology/approach: The study leverages the renowned Carter's 7 C model as a foundational framework for supplier assessment, supplemented by insights gathered from interviews with experts in the New Product Introduction, Purchasing and Procurement departments of a leading hospital in India.
Langmuir
January 2025
Key Laboratory of Green Utilization of Critical Non-Metallic Mineral Resources of Ministry of Education, Wuhan University of Technology, Wuhan 430070, China.
Reverse flotation separation of muscovite from apatite using a dodecylpyridinium chloride (DPDC) ionic liquid as the collector was studied in this work. The microflotation results depicted that DPDC had a strong collecting for muscovite but had a slight collecting for apatite when using phosphoric acid as a depressant for apatite in a weakly acidic pH value pulp, artificial mixture mineral flotation showed that reverse flotation separation of muscovite from apatite can be effectively achieved in the reagent scheme of phosphoric acid/DPDC, and DPDC had a better separation performance in the muscovite/apatite system than DDA. The adsorption measurements indicated that the adsorption amount of DPDC on the apatite surface was less than that of DPDC on the muscovite surface, and the zeta potential results confirmed that a strong interaction occurred between DPDC and the muscovite surface, while an extremely weak interaction occurred between DPDC and the apatite surface in the presence of phosphoric acid at pH ∼ 5.
View Article and Find Full Text PDFJ Cancer Educ
January 2025
Department of Pharmacy, Al Rafidain University College, 10001, Baghdad, Iraq.
Chemotherapy-drug interactions (CDIs) pose significant challenges in oncology, affecting treatment efficacy and patient safety. Despite their importance, there is a lack of validated tools to assess oncologists' knowledge of CDIs. This study aimed to develop and validate a comprehensive questionnaire to address this gap and ensure the reliability and validity of the instrument.
View Article and Find Full Text PDFEur J Pediatr
January 2025
Global Health and Tropical Medicine, GHTM, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, Lisbon, Portugal.
Purpose: Under-five mortality is a key public health indicator, highly responsive to preventive interventions. While global efforts have made strides in reducing mortality rates in this age group, significant disparities persist, particularly in Sub-Saharan Africa. This study aimed to systematically review the factors influencing under-five mortality in Africa, focusing on sociodemographic factors and health-related determinants.
View Article and Find Full Text PDFEnviron Monit Assess
January 2025
Bhaskaracharya College of Applied Sciences, University of Delhi, New Delhi, Delhi, 110078, India.
This study investigates the spatio-temporal distribution of formaldehyde (HCHO) over the mainland Southeast Asian region (including Northeast India) from 2019 to 2022 using TROPOMI satellite data. HCHO is a key atmospheric trace gas which is influenced by both natural processes and anthropogenic activities. We analyze HCHO levels in relation to atmospheric species including carbon monoxide (CO), nitrogen dioxide (NO), and environmental factors such as land surface temperature (LST), precipitation (PPT), fire radiative power (FRP), and enhanced vegetation index (EVI).
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