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Diabetes Ther
February 2025
School of Medicine, Keele University, Staffordshire, UK.
Introduction: We previously reported sex differences in the distribution of glycated haemoglobin (HbA1c) for men/women aged < 50 years vs older individuals, with implications for delayed diabetes diagnosis. Here, we explored whether this pattern was also seen in matched fasting plasma glucose (FPG) levels.
Methods: We extracted data on same-day, paired HbA1c and FPG levels from clinical biochemistry laboratory databases from Mersey and West Lancashire Teaching Hospitals NHS Trust (n = 10,153) and Cambridge University Hospitals NHS Foundation Trust (n = 10,022) between Jan 2019 and Dec 2023.
Schizophr Bull
November 2024
Department of Psychiatry and Psychotherapy, School of Medicine, Technical University of Munich, Munich, Germany.
Background And Hypothesis: The World Health Organization's (WHOs) Mental Health Gap Action Programme (mhGAP) aims to improve healthcare for mental, neurological, and substance use disorders in nonspecialized settings, with a focus on low- and middle-income countries (LMICs). mhGAP includes guidelines for the treatment of psychoses (including schizophrenia), which were recently updated in 2023. The complexity of the WHO guideline update process and the updated recommendations on psychoses are presented.
View Article and Find Full Text PDFBMJ Open
February 2024
Manchester University NHS Foundation Trust, Manchester, UK.
Introduction: The prevalence of gestational diabetes mellitus (GDM) is rising in the UK and is associated with maternal and neonatal complications. National Institute for Health and Care Excellence guidance advises first-line management with healthy eating and physical activity which is only moderately effective for achieving glycaemic targets. Approximately 30% of women require medication with metformin and/or insulin.
View Article and Find Full Text PDFJ Clin Sleep Med
June 2024
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, United Kingdom.
Study Objectives: Obstructive sleep apnea (OSA) is associated with an increased risk of diabetes-related complications. Hence, it is plausible that continuous positive airway pressure (CPAP) could have a favorable impact on these complications. We assessed the feasibility of conducting a randomized control trial in patients with type 2 diabetes and OSA over 2 years.
View Article and Find Full Text PDFDiabetes Ther
February 2024
School of Medicine, Keele University, Keele, ST5 5BG, Staffordshire, UK.
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