Pfizer's Abrysvo vaccine is highly effective in preventing severe lower respiratory tract illness in those at high risk from the Respiratory Syncytial Virus (RSV). Japan, like other countries, is promoting RSV vaccination among pregnant women, but it needs to do better. However, Japan is enduring a state of broad vaccine hesitancy. In light of our experiences with Japan's past failures in promoting the Human Papillomavirus vaccine, we describe some of the challenges encountered in promoting vaccines and discuss possible solutions.

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http://dx.doi.org/10.1016/j.vaccine.2025.126767DOI Listing

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