Understanding the role of mutations in voltage-gated sodium ion channels for cardiovascular disorders.

J Gen Physiol

School of Medicine, Pharmacy and Biomedical Sciences, Faculty of Science & Health, University of Portsmouth, Portsmouth, UK.

Published: March 2025

Elhanafy et al. used Molecular Dynamics simulations and electrophysiology to show how identical mutations in the volgage sending domain of sodium channels can yield differential functional effects.

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Source
http://dx.doi.org/10.1085/jgp.202413744DOI Listing

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