The authors studied the effect of phenazepam, a benzodiazepine derivative, on sleep disorders in alcoholic patients at the first period following alcohol intake discontinuation. Polygraphic registration of the sleep pattern was performed for two nights in 18 patients, receiving the drug and in ten patients of the control group. The drug use was associated with the following events: the latent period of falling asleep diminished, the total duration of sleep increased, the duration of consciousness "inside the sleep" decreased. As a result of the second stage recovery, the duration of the phase of slow sleep enhanced with no evidence of delta-sleep recovery. The duration of the fast sleep phase increased. The patients showed a marked improvement of sleep quality.
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Retina
January 2025
Department of Ophthalmology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Purpose: To evaluate preoperative and early postoperative factors associated with changes in visual acuity in macula-off rhegmatogenous retinal detachment (RRD) patients.
Methods: A retrospective review of 59 eyes from 59 patients who underwent pars plana vitrectomy (PPV) and silicone oil (SiO) tamponade for macula-off RRD. Preoperative and early postoperative characteristics were analyzed using the classification and regression tree (CART) analysis.
Acta Bioeng Biomech
June 2024
2Department of Individual Sports, High Institute of Sport and Physical Education of Ksar Said, Manouba University, Tunisia.
: The acute effects of static stretching (SS) on dynamic balance, a key fitness component that contributes to injury prevention, has been a subject of significant debate. This study aimed to investigate the acute effect of short-duration SS exercises on dynamic balance following different recovery durations in youth female volleyball players. : Thirteen volunteers U-14 female players were included.
View Article and Find Full Text PDFBackground: Chronic obstructive pulmonary disease (COPD) patients commonly exhibit significant morbidity and experience a diminished quality of life. Since there has been no prior research on pneumonia in our study population, we carried out this study to learn more about the situation.
Methods: A retrospective analysis of 912 COPD patients with CAP who were receiving ICS treatment at the DHQ Hospital in Muzaffargarh, Punjab, Pakistan was conducted.
J Intensive Med
January 2025
Medical Intensive Care Unit, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Beijing, China.
Background: Receptor-interacting protein kinase 1 (RIPK1), a serine/threonine protein kinase, is mainly activated by pro-inflammatory cytokines and pathogens, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and its activation could result in apoptosis, necroptosis, or inflammation. This study was conducted to evaluate the safety and efficacy of a potent and selective inhibitor of RIPK1, SIR1-365, in hospitalized patients with severe coronavirus disease 2019 (COVID-19).
Methods: This multicenter, randomized, double-blind, phase 1b study screened patients from December 18, 2020 until November 27, 2021.
World J Gastrointest Surg
January 2025
Department of General Surgery, Chongqing General Hospital, Chongqing 401120, China.
Background: There is an increased maturation of laparoscopic intracorporeal anastomosis techniques. However, research on its application for small bowel stoma reversal in patients with Crohn's disease (CD) is limited. Therefore, in this study, we compared the perioperative outcomes between laparoscopic intracorporeal ileostomy reversal (LIIR) and open ileostomy reversal (OIR).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!