The author analyzes the findings of a long-term follow-up of 70 patients with neurosis-like forms of organic diseases of the brain (arachnoiditis, encephalitides, diencephalitides). The time-course was evaluated by the clinical improvement and by the improvement in the patient's social functioning. Three groups of patients were identified with regard to a definite type of the personal response to the disease and to specific features of social and occupational adaptation. It was demonstrated that the distribution of patients into groups and thus their clinical and socio-occupational prognosis was largely determined by the psychogenic-neurotic component of the illness rather than by the severity of the organic lesion.

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