Surgery of lesions around Wernicke's area is challenging for several reasons. The anatomical boundaries are not clearly defined, necessitating functional identification in addition to anatomical landmarks. There are potential complications secondary to injury of the surrounding structures. This challenge is more substantial when dealing with lower-grade gliomas in this region, as surgeons must balance the extent of resection with the risk of potential injury to the patient, especially considering that there may be other treatment options for the management of residual tumors. In this video, the authors present a case illustration, discussing surgical considerations and strategy. The video can be found here: https://stream.cadmore.media/r10.3171/2024.10.FOCVID24101.
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http://dx.doi.org/10.3171/2024.10.FOCVID24101 | DOI Listing |
Neurosurg Focus Video
January 2025
Department of Neurosurgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan; and.
Surgery of lesions around Wernicke's area is challenging for several reasons. The anatomical boundaries are not clearly defined, necessitating functional identification in addition to anatomical landmarks. There are potential complications secondary to injury of the surrounding structures.
View Article and Find Full Text PDFNeuroimage
January 2025
Department of Anthropology, The George Washington University, Washington DC, USA.
Broca's and Wernicke's areas are comprised of Brodmann areas 44, 45 and 22 in the human brain. Because of their roles in higher cognitive and linguistic function, there has been historical and contemporary interest in comparative studies on the morphology and cytoarchitectonic organization in Broca's and Wernicke's between primate species. One challenge to comparative morphological studies between human and nonhuman primates for Broca's and Wernicke's areas is the absence in homologous sulci used to define these regions.
View Article and Find Full Text PDFObjective: Functional MRI (fMRI) helps with the identification of eloquent cortex to assist with function preservation in patients who undergo epilepsy surgery. Language and memory tasks can even be used effectively in clinically involved pediatric patients. Most pediatric studies report on English speaking-only cohorts from English-dominant countries, yet languages other than English (LOEs) are increasingly prevalent in countries such as the US.
View Article and Find Full Text PDFNeurology
December 2024
From the Department of Neurology, Vanderbilt University Medical Center, Nashville, TN.
Background And Objectives: Frontotemporal lobar degeneration (FTLD) includes different clinical syndromes with distinct patterns of symptoms and neuroanatomical locations of neurodegeneration. However, FTLD is clinically heterogeneous (with overlapping symptoms across several domains) and neuroanatomically heterogeneous (with brain atrophy in different locations in different patients). Traditional methods struggle to fully account for this heterogeneity.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!