Electrophysiological mapping and monitoring techniques permit the objective measurement of eloquent cortical regions and accompanying white matter tracts to reduce the incidence of iatrogenic injury in glioma surgery. Recently, there has been increased interest in mapping and monitoring of the human arcuate fasciculus via cortico-cortical evoked potentials (CCEPs) during awake and asleep craniotomy. The authors present the case of a 27-year-old female who underwent a hypnosis-assisted awake craniotomy with cortico-subcortical language mapping and arcuate fasciculus CCEPs. There were no adverse effects associated with CCEP monitoring. Further investigation is required in order to substantiate the technique and validate clinical significance criteria, which may reliably permit asleep language mapping and monitoring. The video can be found here: https://stream.cadmore.media/r10.3171/2024.10.FOCVID24126.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748948 | PMC |
| http://dx.doi.org/10.3171/2024.10.FOCVID24126 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Arcuate fasciculus cortico-cortical evoked potentials and direct cortico-subcortical stimulation during awake craniotomy for debulking of left dominant temporal oligodendroglioma.
Neurosurg Focus Video
January 2025
Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Adelaide, South Australia; and.
Electrophysiological mapping and monitoring techniques permit the objective measurement of eloquent cortical regions and accompanying white matter tracts to reduce the incidence of iatrogenic injury in glioma surgery. Recently, there has been increased interest in mapping and monitoring of the human arcuate fasciculus via cortico-cortical evoked potentials (CCEPs) during awake and asleep craniotomy. The authors present the case of a 27-year-old female who underwent a hypnosis-assisted awake craniotomy with cortico-subcortical language mapping and arcuate fasciculus CCEPs.
View Article and Find Full Text PDFNeonatal inflammation and near-term white matter microstructure in infants born very preterm.
Neuroimage Rep
December 2024
Department of Pediatrics, Division of Developmental-Behavioral Pediatrics, Stanford University, Stanford, CA, USA.
Background: Severe neonatal inflammatory conditions in very preterm infants (VPT: <32 weeks gestational age, GA) are linked to adverse neurodevelopmental outcomes. Differences in white matter (WM) microstructure of the corpus callosum (CC) have been observed at age 6 in VPT children with a history of severe neonatal inflammation. The goal of this study was to determine whether these CC differences can be detected at term-equivalent age using diffusion MRI (dMRI), and whether neonatal inflammation is associated with altered WM in additional tracts implicated in the encephalopathy of prematurity.
View Article and Find Full Text PDFTay-Sachs and Sandhoff Diseases: Diffusion tensor imaging and correlational fiber tractography findings differentiate late-onset GM2 Gangliosidosis.
medRxiv
December 2024
Office of the Clinical Director and Medical Genetics Branch, National Human Genome Research Institute, 10 Center Drive, Bethesda MD USA.
GM2 gangliosidosis is lysosomal storage disorder caused by deficiency of the heterodimeric enzyme β-hexosaminidase A. Tay-Sachs disease is caused by variants in encoding the α-subunit and Sandhoff disease is caused by variants in encoding the β-subunit. Due to shared clinical and biochemical findings, the two have been considered indistinguishable.
View Article and Find Full Text PDFChanging the Paradigm for Tractography Segmentation in Neurosurgery: Validation of a Streamline-Based Approach.
Brain Sci
December 2024
Neuroinformatics Laboratory (NiLab), Bruno Kessler Foundation (FBK), 39123 Trento, Italy.
In glioma surgery, maximizing the extent of resection while preserving cognitive functions requires an understanding of the unique architecture of the white matter (WM) pathways of the single patient and of their spatial relationship with the tumor. Tractography enables the reconstruction of WM pathways, and bundle segmentation allows the identification of critical connections for functional preservation. This study evaluates the effectiveness of a streamline-based approach for bundle segmentation on a clinical dataset as compared to the traditional ROI-based approach.
View Article and Find Full Text PDFAdvanced disconnectomic analyses reveal repetition pathways in a case of mixed transcortical aphasia.
Brain Cogn
February 2025
Department of Neuroscience, University of Padova, Italy; Padova Neuroscience Center, University of Padova, Italy. Electronic address:
Mixed Transcortical Aphasia (MTA) is an infrequent aphasic syndrome, characterized by poor comprehension and production in oral language abilities and poor performance in written language abilities. However, individuals with MTA typically retain the ability to repeat. Our patient, a woman who suffered from a left hemisphere ischemic stroke involving perisylvian areas, presented with repetition preserved for words, non-words, sentences and numbers, together with marginally preserved reading abilities.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!