Background: In the context of modern oncology, radiogenic elements have emerged as pivotal tools for targeted cancer therapies. Elements like Iodine-131 and Yttrium-90 offer unique radiological properties that allow precise treatment delivery. This article explores their growing importance and potential in reshaping the landscape of cancer therapy.
Methods: Utilizing a systematic literature search, relevant studies, clinical trials, and research articles were collected from databases. The selected material was scrutinized to extract insights into the mechanisms, applications, advantages, and challenges of radiogenic elements. These results are combined in the study to give a perceptive picture of how contemporary oncology treatment is developing.
Results: The article reveals a comprehensive analysis of the outcomes derived from the study of radiogenic elements in contemporary cancer treatment. The results highlight the diverse applications of radionuclides like Iodine-131, Yttrium-90, and actinides in targeted therapies. It showcases their ability to selectively damage cancer cells while sparing healthy tissues, emphasizing precision and efficacy. The review underscores the increasing importance of personalized medicine, combination therapies, and the potential of emerging alpha-particle-based treatments. Furthermore, the results shed light on the challenges posed by radiation safety and potential side effects, prompting a need for vigilant management. This comprehensive examination of results provides a nuanced understanding of the pivotal role that radiogenic elements play in shaping the future of modern oncology therapy.
Conclusion: The article examines the role of radiogenic elements in contemporary cancer treatment. It highlights the significance of elements like 131I, 90Y, and actinides in targeted therapies, discussing their mechanisms and applications. The article emphasizes personalized medicine, combination therapies, and emerging alpha-particle-based treatments. Challenges, including radiation safety and side effects, are also addressed. The review anticipates a promising future where radiogenic elements contribute to precise, effective, and patient-centered cancer care.
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http://dx.doi.org/10.2174/0118744710337420250102054532 | DOI Listing |
Curr Radiopharm
January 2025
Apollonia" University of Iasi, Faculty of Dental Medicine, 11 Pacurari Str., 700511, Iasi, Romania.
Background: In the context of modern oncology, radiogenic elements have emerged as pivotal tools for targeted cancer therapies. Elements like Iodine-131 and Yttrium-90 offer unique radiological properties that allow precise treatment delivery. This article explores their growing importance and potential in reshaping the landscape of cancer therapy.
View Article and Find Full Text PDFSci Data
January 2025
Department of Archaeology, Max Planck Institute of Geoanthropology, Jena, 07745, Germany.
Here, we present the North American Repository for Archaeological Isotopes (NARIA), the largest open-access compilation of previously reported isotopic measurements (n = 28,374) from bioarchaeological samples in North America (i.e., Canada, Greenland, Mexico, and the United States of America) covering a time-frame of more than 12,000 years.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Cosmochemistry and Isotope Signatures Group Nuclear and Chemical Sciences Division Lawrence Livermore National Laboratory, Livermore, CA 94550.
The radiogenic isotopic compositions of basaltic Martian meteorites (shergottites) and clinopyroxene/olivine cumulate meteorites (nakhlite/chassignites) are used to define the global evolution of Mars. However, the two main groups of meteorites demonstrate that their sources underwent divergent styles of magmatic evolution. The shergottites portray a planet that differentiated ~4.
View Article and Find Full Text PDFNat Commun
December 2024
Anthropology Department, University of California Santa Cruz, Santa Cruz, CA, USA.
Strontium isotope (Sr/Sr) analysis with reference to strontium isotope landscapes (Sr isoscapes) allows reconstructing mobility and migration in archaeology, ecology, and forensics. However, despite the vast potential of research involving Sr/Sr analysis particularly in Africa, Sr isoscapes remain unavailable for the largest parts of the continent. Here, we measure the Sr/Sr ratios in 778 environmental samples from 24 African countries and combine this data with published data to model a bioavailable Sr isoscape for sub-Saharan Africa using random forest regression.
View Article and Find Full Text PDFSci Total Environ
January 2025
Laboratoire G-Time, Department of Geosciences, Environment and Society, Université Libre de Bruxelles, ULB, CP 160/02, Avenue F.D. Roosevelt, 50, B-1050 Brussels, Belgium.
Effective methods for measuring sudden environmental changes are crucial for understanding how cities respond to shifts in human activity. This study examines atmospheric metal outputs during the COVID-19 restrictions using honey samples collected from three land use types in Brussels Capital Region (BCR), Belgium, and Metro Vancouver Regional District (MVRD), Canada to study changes as the result of restrictions. By comparing these cities with distinct sizes, ages, and structures, we assess how urban environments responded to pandemic-induced restrictions.
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