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First pilot study for newborn screening of severe T and B lymphopenias in Colombia.
Biomedica
December 2024
Grupo de Inmunodeficiencias Primarias, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Introduction: Congenital lymphopenias cause increased susceptibility to infections in children apparently healthy at birth. Earlier detection of these conditions would facilitate prompt treatment, prevent potentially serious disease complications and early deaths, and save healthcare resources.
Objective: To perform a pilot study for neonatal screening of congenital lymphopenias by the quantification of TREC and KREC –T- and B-cell receptor excision circles– in peripheral blood samples from newborns in Medellín, Colombia.
Modifications to the Geriatric Nutritional Risk Index Predicts Complications after Total Joint Arthroplasty.
J Arthroplasty
January 2025
Virginia Tech Carilion School of Medicine, 2 Riverside Circle, Roanoke, Virginia, 24016, United States of America; Department of Orthopaedic Surgery, Carilion Clinic Institute for Orthopaedics & Neurosciences, 2331 Franklin Road Southwest, Roanoke, Virginia, 24014, United States of America.
Background: Preoperative malnutrition is a known risk factor for postoperative complications following total joint arthroplasty (TJA), however, there is scant literature comparing which nutritional index is best at predicting these outcomes. The purpose of this study was to investigate the utility of the Maastricht Index (MI), Onodera's Prognostic Index (OPNI), the Geriatric Nutritional Risk Index (GNRI), and a novel, modified Geriatric Nutritional Risk Index (mGNRI) in predicting periprosthetic joint infection (PJI), wound complications (WC), readmission, and reoperation rates after TJA.
Methods: A single-center, retrospective cohort study was performed of patients who underwent primary TJA from January 2016 to December 2021.
A morphology of the distal medial femoral surface that should be considered when performing coronal osteotomy in medial closed wedge distal femoral varus osteotomy.
Knee
December 2024
Department of Orthopaedic Surgery, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japan.
Aims: The aim of the present study was to evaluate the morphology of the distal medial femoral surface during coronal osteotomy in medial closed wedge distal femoral varus osteotomy (MCWDFO) using plain CT.
Methods: Twenty knees (mean age, 55.3 years) were included.
Background: In low- and middle-income countries (LMICs), laparoscopic surgery is challenging to implement due to limited resources and lack of expert surgeons as teachers. The Global Laparoscopic Advancement Program (GLAP) was developed by the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) to deliver sustainable and effective methods for teaching safe laparoscopic surgery. GLAP aims to train surgical leaders and trainees with the goal of eventual in-country replication of GLAP programming.
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