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Plant Extracellular Nanovesicle-Loaded Hydrogel for Topical Antibacterial Wound Healing .
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Department of Chemistry, Shiv Nadar Institution of Eminence, Delhi-NCR, Uttar Pradesh 201314, India.
Bacterial infections impede wound healing and pose significant challenges in clinical care. There is an immediate need for safe and targeted antivirulence agents to fight bacterial infections effectively. In this regard, bioderived nanovesicles have shown significant promise.
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Laboratory of Chromatin Biology & Epigenetics, Indian Institute of Science Education and Research, Pune, India.
Background: Statins, frequently prescribed medications, work by inhibiting the rate-limiting enzyme HMG-CoA reductase (HMGCR) in the mevalonate pathway to reduce cholesterol levels. Due to their multifaceted benefits, statins are being adapted for use as cost-efficient, safe and effective anti-cancer treatments. Several studies have shown that specific types of cancer are responsive to statin medications since they rely on the mevalonate pathway for their growth and survival.
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Department of Chemistry, Shiv Nadar University, Greater Noida, 201314, India.
Tuberculosis (TB) is a serious communicative disease caused by Mycobacterium tuberculosis. Although there are vaccines and drugs available to treat the disease, they are not efficient, moreover, multidrug-resistant TB (MDR-TB) become a major hurdle in its therapy. These MDR strains utilize the multidrug efflux pump as a decisive weapon to fight against antitubercular drugs.
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Biorefining and Advanced Materials Research Center, SRUC, Edinburgh EH9 3JG, UK.
The exploration of multiplexed bacterial virulence factors is a major problem in the early stages of infection therapy. Traditional methods for detecting (, such as serological experiments, immunoassays, polymerase chain reaction, and isothermal microcalorimetry have some drawbacks. As a result, detecting in a timely, cost-effective, and sensitive manner is critical for various areas of human safety and health.
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