The efficacy of traceability analysis is often limited by a lack of information on influencing factors for heavy metal (HM) contaminations in soil, such as spatial correlations between HM concentrations and influencing factors. To overcome this limitation, a novel data-driven framework was established to identify influencing factors for soil HM concentrations in an industrialised study area, in Guangdong Province, China, mainly using random forest (RF) and bivariate local Moran's I (BLMI) on the basis of the 577 soil samples and the 18 environmental covariates. The quantitative contributions of the 18 influencing factors for the Cd, As, Pb, and Cr concentrations were determined by the optimised RF. The main influencing factors of Cd were petrol stations (10.97%) and railways (9.99%), the main ones of As were groundwater depth (8.45%) and elevation (8.24%), the main ones of Pb were soil pH (8.82%) and hazardous waste disposal sites (8.02%), and the main ones of Cr were mine tailings (13.65%) and rainfall (11.88%). The eight spatial clustering maps between the four HM concentrations and the two key influencing factors were generated by BLMI. The middle part of the study area has shown the higher concentrations of Cd, As, Pb, and Cr, the more complex human activities and the more high-high clusters. Priority attention should be paid to the middle part when taking the specific prevention and control measures for their contaminations. This data-driven framework provided rich information on influencing factors, including HM concentrations, HM contaminations, quantitative contributions, and qualitative spatial clusters.
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http://dx.doi.org/10.1016/j.jenvman.2025.124172 | DOI Listing |
Objective: Scleroderma-associated autoantibodies (SSc-Abs) are specific in participants (pts) with systemic sclerosis and are associated with organ involvement. Our objective was to assess the influence of baseline SSc-Abs on the trajectories of the clinical outcome assessments (COAs) in a phase III randomized controlled trial.
Methods: We used data on both the groups who received placebo (Pbo) and tocilizumab from the focuSSced trial.
Zool Res
January 2025
Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. E-mail:
Animal adaptation to environmental challenges is a complex process involving intricate interactions between the host genotype and gut microbiome composition. The gut microbiome, highly responsive to external environmental factors, plays a crucial role in host adaptability and may facilitate local adaptation within species. Concurrently, the genetic background of host populations influences gut microbiome composition, highlighting the bidirectional relationship between host and microbiome.
View Article and Find Full Text PDFAnn Surg
January 2025
Hubei Key Laboratory of Ischemic Cardiovascular Disease, Yichang, China.
Objective: The aim of this study is to explore the risk profiles associated with Abdominal aortic aneurysm (AAA) incidence in both the general population and diverse subpopulations.
Summary Background Data: AAA is a life-threatening arterial disease, and there is limited understanding of its etiological spectrum across the age, sex, and genetic risk subgroups, making early prevention efforts more complicated.
Methods: This study encompassed a sample size of 364399 participants from the UK.
Nurs Open
January 2025
Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
Aim: The present study was conducted to determine the effect of non-pharmacological interventions before cataract surgery on preoperative anxiety.
Design: Systematic review and meta-analysis.
Methods: Five databases were systematically searched until 9 June, 2024.
Glob Epidemiol
June 2025
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Introduction: Opium and cigarette smoking have been identified as significant cancer risk factors. Recently, the International Agency for Research on Cancer (IARC) classified opium as a Group 1 carcinogen in 2020.
Method: Using data from a multicenter case-control study in Iran called IROPICAN, involving 717 cases of bladder cancer and 3477 controls, we assessed the interactions on the causal additive scale between opium use and cigarette smoking and their attributing effects to evaluate public health relevance and test for different mechanistic interaction forms to provide new insights for developing of bladder cancer.
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