Purpose: Digital Breast Tomosynthesis (DBT) is an advanced mammography technique for which there are currently no internationally agreed methods and reference values for image quality assessment. The aim of this multicentre study was to evaluate a simple method to assess the technical image quality of reconstructed and synthetic 2D (SM) images of different models of DBT systems using commercially available phantoms.
Methods: The signal difference to noise ratio (SDNR) was chosen as an index of technical image quality and was evaluated for three commercial phantoms, Tomophan, Tormam and CIRS model 015, on 55 DBT systems (six vendors, nine models).
Results: SDNR was found to depend on several factors: detail size, average glandular dose (AGD), reconstruction algorithm, software version and applied post-processing. In particular, an increase in SDNR was observed with increasing detail size, AGD, as well as with the use of contrast-enhanced post-processing and iterative reconstruction algorithms. Most systems showed higher SDNR values in SM images respect to DBT for the largest details and a decrease for smaller details.
Conclusions: This study proposes a straightforward method to assess the technical image quality of reconstructed DBT and SM images using three different commercial phantoms. The algorithms used to generate SM and DBT images might perform differently when applied to phantoms with homogeneous backgrounds compared to clinical breast structures. However this method could be used to establish reference values for technical image quality during quality control (QC) which could be used to monitor the consistency of the system's performance over time.
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http://dx.doi.org/10.1016/j.ejmp.2025.104907 | DOI Listing |
J Pathol
January 2025
The Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.
Spatial transcriptomics (ST) offers enormous potential to decipher the biological and pathological heterogeneity in precious archival cancer tissues. Traditionally, these tissues have rarely been used and only examined at a low throughput, most commonly by histopathological staining. ST adds thousands of times as many molecular features to histopathological images, but critical technical issues and limitations require more assessment of how ST performs on fixed archival tissues.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Beijing Key Laboratory of Construction-Tailorable Advanced Functional Materials and Green Applications Experimental Center of Advanced Materials, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China.
Metal halide perovskites (MHPs) are promising materials for radiation detection. Compared with polycrystalline films, single crystals (SCs) have lower defect density, higher carrier mobility, and lifetime. However, the direct synthesis of MHP SCs for large-area flat panel imaging detectors remains challenging.
View Article and Find Full Text PDFMagn Reson Med
January 2025
MR Physics, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Purpose: MR-based FID navigators (FIDnavs) do not require gradient pulses and are attractive for prospective motion correction (PMC) due to short acquisition times and high sampling rates. However, accuracy and precision are limited and depend on a separate calibration measurement. Besides FIDnavs, stationary NMR field probes are also capable of measuring local, motion-induced field changes.
View Article and Find Full Text PDFEur Heart J Digit Health
January 2025
Department of Cardiovascular Surgery of Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Aims: Accurate heart function estimation is vital for detecting and monitoring cardiovascular diseases. While two-dimensional echocardiography (2DE) is widely accessible and used, it requires specialized training, is prone to inter-observer variability, and lacks comprehensive three-dimensional (3D) information. We introduce CardiacField, a computational echocardiography system using a 2DE probe for precise, automated left ventricular (LV) and right ventricular (RV) ejection fraction (EF) estimations, which is especially easy to use for non-cardiovascular healthcare practitioners.
View Article and Find Full Text PDFBackground And Aims: Pectus carinatum (PC) is the second most common deformity of the anterior chest wall, resulting in detrimental effects on body image and quality of life. This study evaluated the safety, effectiveness, and factors associated with the treatment of PC using a sandwiched bar and screw fixation system, first performed in Vietnam at the University Medical Center Ho Chi Minh City in 2016.
Methods: This retrospective cohort study was conducted from March 2016 to February 2023 in patients with PC and PC-mixed pectus excavatum (PE) deformities.
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