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Risk Factors for Symptoms in Patients With Heterotopic Gastric Mucosa in the Upper Esophagus.

Gastroenterol Res Pract

January 2025

Department of Gastroenterology, Tongji Institute of Digestive Diseases, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.

This study is aimed at comparing the clinical characteristics and histological types of symptomatic and asymptomatic patients with heterotopic gastric mucosa in the upper esophagus (HGMUE) and exploring the factors influencing the occurrence and severity of laryngopharyngeal reflux (LPR) symptoms in these patients. HGMUE is a potential cause of LPR symptoms. This retrospective analysis evaluated 70 patients with HGMUE using a detailed questionnaire.

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Heterogeneity of pancreatic neoplasms arising in pancreatic heterotopia: a single institution review.

Virchows Arch

November 2024

Department of Pathology and Immunology, Washington University in St. Louis, 660 South Euclid Avenue, Campus, Box 8118, St. Louis, MO, 63110, USA.

Article Synopsis
  • Pancreatic heterotopia (PH) is when pancreatic tissue forms in the gastrointestinal tract and can have various health issues, though cancer development in PH is very uncommon.
  • A study reviewed 163 PH cases from 1990 to 2020, finding that 7 had neoplastic processes, including different types of tumors.
  • Most affected patients were men around 64 years old, with symptoms such as weight loss and abdominal pain, and it’s critical for pathologists to identify PH to ensure correct diagnosis and staging of potential tumors.
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Heterotopia or ectopic tissue refers to the presence of normal tissue in an abnormal location, away from its typical anatomic site. While heterotopia is not uncommon, its occurrence in the gallbladder is quite rare, and even more unusual is the presence of gastric heterotopia within the gallbladder. This case report describes a 41-year-old female patient with oxyntic-type heterotopic gastric mucosa in the proximal body of the gallbladder.

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Pancreatic heterotopia is the presence of pancreatic tissue in a different anatomical location with no connection to the main pancreas. The most common locations in the gastrointestinal system are duodenum, stomach, and Meckel diverticulum. However, it is quite rare in the hepatobiliary system.

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