Aim: To assess the changes of intracranial pressure waveforms (ICPW) acquired noninvasively in a set of acute hydrocephalus patients prior to and posterior to interventions.
Material And Methods: Patients with clinical and radiological diagnosis of hydrocephalus were evaluated for alterations in ICPW by means of a system that detects cranial micro expansions just before and immediately after interventions. The system quantified the difference between ICPW peaks (P1 and P2), providing the P2/P1 ratio.
Results: Fourteen patients aged from 26 to 73 years old met the inclusion criteria. Hydrocephalus etiologies were normal pressure hydrocephalus, post-traumatic and all patients had an abnormal intracranial compliance waveform, with P2 > P1 before the procedure (5 external ventricular drains (EVD) and 9 ventriculoperitoneal shunts (VPS). Immediately after, 75% of the patients changed to a standard pattern with P1 > P2.
Conclusion: In this exploratory study using a novel noninvasive technique, rapid cerebrospinal fluid drainage by means of EVD and VPS was effectively assessed and had a positive impact on intracranial compliance.
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http://dx.doi.org/10.5137/1019-5149.JTN.45668-23.2 | DOI Listing |
Cureus
December 2024
Department of Neurosurgery, International University of Health and Welfare Narita Hospital, Narita, JPN.
Infectious intracranial aneurysms (IIAs) are rare lesions with fragile arterial walls located within the aneurysms, carrying a high risk of rupture. Standard management often involves antibiotic therapy and parent artery occlusion; however, the latter carries a significant risk of cerebral infarction. This report presents a case of an unruptured IIA following cerebral infarction, successfully treated with coil embolization while preserving the parent artery.
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December 2024
Emergency, Royal Victorian Eye and Ear Hospital, Melbourne, AUS.
Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by chronic headaches, cognitive difficulties, reduced quality of life, and rarely irreversible visual loss. Community diagnosis is often challenging due to unfamiliarity with current guidelines and a lack of clinical experience, leading to misdiagnosis and treatment delays, which can negatively impact visual recovery and quality of life. Our study examined the time to diagnosis and investigated the barriers to timely diagnosis in adults with newly diagnosed IIH.
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December 2024
Internal Medicine, Pedro Hispano Hospital, Matosinhos Local Health Unit, Matosinhos, PRT.
Intracranial complications of otitis media are rare but pose a significant risk of morbidity and mortality. We report a case of a 27-year-old man with cognitive impairment who presented with fever, right-sided otalgia, otorrhea, and vomiting for three days. His neurological examination was unremarkable, and a brain computed tomography (CT) revealed right-sided otomastoiditis without intraparenchymal lesions.
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January 2025
Emergency Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, USA.
Anticholinergic toxicity typically presents with symptoms of cutaneous vasodilation, delirium, mydriasis, urinary retention, hyperthermia, anhidrosis, and tachycardia. This case report presents a 68-year-old female patient who exhibited some of these signs and symptoms after ingesting an unknown quantity of dicyclomine. However, she displayed one notable exception to the classic toxidrome.
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December 2024
Pulmonary and Critical Care, Jackson Memorial Hospital, Miami, USA.
Cancer and antiphospholipid syndrome (APS) independently increase thrombotic risk, and their coexistence can create a particularly hazardous prothrombotic state. This case report aims to highlight the complex challenges in managing concurrent thrombotic and hemorrhagic events in patients with a history of cancer and APS. The combination of these conditions presents a rare and difficult clinical scenario, requiring careful consideration in anticoagulation management.
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