Objective: To explore the effects of donor sperm on reproductive quality of life, sleep quality and erectile function in patients with severe oligoasthenospermia after the failure of intracytoplasmic sperm injection (ICSI), and to provide targeted reference for intervention.
Methods: From January 2021 to December 2023, patients with severe oligoasthenospermia who received assisted pregnancy treatment in Obstetrics and Gynecology Hospital Affiliated to Tongji University were selected as the study objects. Among them, 82 cases using sperm donor assisted pregnancy after ICSI failure were set as the observation group, and 82 cases using propensity score 1:1 matching ICSI failure after ICSI assisted pregnancy were set as the control group. The levels of serum total testosterone, reproductive quality of life, sleep quality and erectile function of the two groups were compared using the general data questionnaire, FertiQoL, Pittsburgh Sleep Quality Index (PSQI) and International erectile Function Index -5(IIEF-5).
Results: There was no significant difference in social demographic data and serum total testosterone level between the two groups after matching propensity score (>0.05). The total score of FertiQoL and PSQI in the observation group were higher than those in the control group, and the incidence of erectile dysfunction was higher than that in the control group, with statistical significance (<0.05).
Conclusion: The use of donor sperm for pregnancy after ICSI failure in patients with severe oligoasthenospermia has a great impact on their reproductive life, sleep quality and erectile function. Medical staff should pay attention to the quality of life and erectile function of these patients, and formulate targeted measures to help these patients cope positively.
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http://dx.doi.org/10.2147/JMDH.S494319 | DOI Listing |
J Obstet Gynaecol Res
January 2025
Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
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Head Neck
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Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
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Front Plant Sci
January 2025
College of Agronomy and Life Sciences, Zhaotong University, Zhaotong, China.
Environmental conditions significantly influence the metabolic composition and quality attributes of fruits. This study investigated the impact of altitude-associated environmental variation on flavonoid profiles and fruit quality parameters by comparing the "Red Face" strawberry variety grown in two distinct locations: high-altitude-associated environmental conditions in Zhaotong and low-altitude conditions in Dandong. Using LC-MS/MS analysis, we identified 163 bioactive flavonoids, comprising 85 flavonols, 37 flavanones, 33 flavones, and 8 flavanonols.
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