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| http://dx.doi.org/10.1016/j.jdcr.2024.10.009 | DOI Listing |
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Diffuse pustules overlying brightly erythematous plaques in skin of color.
JAAD Case Rep
February 2025
Harvard Medical School, Boston, Massachusetts.
Effective Management of Severe Epidermal Growth Factor Receptor Inhibitors-Induced Papulopustular Eruption With Low-Dose Isotretinoin and Corticosteroids.
Cureus
November 2024
Oncologic Dermatology, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU.
Epidermal growth factor receptor inhibitors (EGFRi) are approved for treating various cancers. Given that EGFR signaling is crucial for normal skin growth and repair, inhibiting this pathway can disrupt skin homeostasis and integrity. Although generally well tolerated, molecularly targeted therapies can lead to skin-related adverse effects that significantly impact patients' quality of life, often resulting in treatment interruptions.
View Article and Find Full Text PDFSevere allergic rash induced by icodextrin: case report and literature review.
Front Med (Lausanne)
October 2024
Department of Nephrology, Shaoxing Second Hospital, Shaoxing, Zhejiang, China.
Background: Icodextrin is a type of peritoneal dialysis (PD) osmolyte that can be extended retention times (8-16 h) and may offer a viable alternative to conventional glucose dialysis solutions for PD patients. Nonetheless, prolonged use of icodextrin may lead to allergic rash, and rarely severe skin lesions.
Case Presentation: In February 2024, a 45-year-old male was admitted to the Department of Nephrology at Shaoxing Second Hospital presenting with a 3-day history of intense generalized pruritic erythematous rash.
Dermoscopic Features of Dermatitis Cruris Pustulosa et Atrophicans: A Retrospective Study from a Tertiary Care Center in South India.
Indian Dermatol Online J
August 2024
Department of Dermatology and STD, National Institute of Medical Sciences and Research, Jaipur, Rajasthan, India.
Article Synopsis
- Dermatitis cruris pustulosa et atrophicans (DCPA) is a chronic skin condition that can lead to hair loss if not treated and is characterized by certain dermoscopic features that distinguish it from similar conditions.
- A study conducted on 30 patients in South India identified key dermoscopic findings such as follicular pustules, white structureless areas around follicles, and various vascular patterns, confirming the prevalence of DCPA in males and primarily affecting the lower limbs.
- Limitations of the study included its retrospective nature, small sample size, and absence of a comparison group, highlighting the need for further research to better understand DCPA and its features.
Acute generalized exanthematous pustulosis induced by icotinib: a case report and literature review.
Front Pharmacol
August 2024
Department of Dermatology, General Hospital of Northern Theater Command, Shenyang, China.
Acute generalized exanthematous pustulosis, an infrequent adverse drug reaction, mainly results from drugs. Clinically, acute generalized exanthematous pustulosis manifests as a high fever, with skin lesions of small monomorphic subcorneal sterile pustules on an erythematous that presents at 1-4 days after medication exposure. The incidence of acute generalized exanthematous pustulosis varies from 3/1, 000, 000 to 5/1, 000, 000, while the mortality rate is typically around 5%.
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