Mountain ecosystems harbor high levels of biodiversity, but the genetic mechanisms underlying adaptation to harsh alpine conditions remain largely unknown. Bergenia purpurascens (Saxifragaceae) is an important alpine endemic species of the Himalaya-Hengduan Mountains (HHM), with this species being used as a source of medicine and as an ornamental plant. In this study, we generated a high-quality genome assembly comprising scaffolds representing the 17 chromosomes, with a total length of 650.70 Mb and a scaffold N50 of 34.19 Mb. A total of 45,841 protein-coding genes were annotated, and 10,797 noncoding RNAs were identified. Repeat sequences accounted for 56.72% of the genome. The reference genome of B. purpurascens serves as a valuable resource for studying bergenin biosynthesis, and understanding adaptation of plants to alpine environments.
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http://dx.doi.org/10.1038/s41597-025-04473-3 | DOI Listing |
Wellcome Open Res
November 2024
Lancaster Environment Centre, Lancaster University, Lancaster, England, UK.
We present a genome assembly from a juvenile male (the white-throated dipper; Chordata; Aves; Passeriformes; Cinclidae). The genome sequence has a total length of 1,170.80 megabases.
View Article and Find Full Text PDFISME Commun
January 2025
Department of Microbiology, Universität Potsdam, Institute of Biochemistry and Biology, 14476 Potsdam-Golm, Germany.
The cyanobacterium causes harmful algal blooms that pose a major threat to human health and ecosystem services, particularly due to the prevalence of the potent hepatotoxin microcystin (MC). With their pronounced EPS layer, colonies also serve as a hub for heterotrophic phycosphere bacteria. Here, we tested the hypothesis that the genotypic plasticity in its ability to produce MC influences the composition and assembly of the phycosphere microbiome.
View Article and Find Full Text PDFVirus Evol
January 2025
Institute of Western Agriculture, Chinese Academy of Agricultural Sciences, Changji 831100, China.
Advancements in high-throughput sequencing and associated bioinformatics methods have significantly expanded the RNA virus repertoire, including novel viruses with highly divergent genomes encoding "orphan" proteins that apparently lack homologous sequences. This absence of homologs in routine sequence similarity search complicates their taxonomic classification and raises a fundamental question: Do these orphan viral genomes represent viruses? In 2022, an orphan viral genome encoding a large polyprotein was identified in alfalfa () and thrips (), and named Snake River alfalfa virus (SRAV). SRAV was initially proposed as an uncommon flavi-like virus identified in a plant host distantly related to family .
View Article and Find Full Text PDFFront Microbiol
January 2025
Institute of Microbiology, University of Agriculture, Faisalabad, Pakistan.
Background: Colistin is an antibiotic used as a last resort to treat multidrug-resistant Gram-negative bacterial infections. Plasmid-mediated mobile colistin-resistant () genes in () are disseminated globally and are considered to be a major public health threat. This study aimed to determine the molecular characteristics of colistin-resistant isolates in clinical settings in Pakistan.
View Article and Find Full Text PDFBMC Biol
January 2025
Oniris, INRAE, BIOEPAR, 44300, Nantes, France.
Background: Ticks, hematophagous Acari, pose a significant threat by transmitting various pathogens to their vertebrate hosts during feeding. Despite advances in tick genomics, high-quality genomes were lacking until recently, particularly in the genus Ixodes, which includes the main vectors of Lyme disease.
Results: Here, we present the genome sequences of four tick species, derived from a single female individual, with a particular focus on the European species Ixodes ricinus, achieving a chromosome-level assembly.
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