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Neuraxial biomechanics, fluid dynamics, and myodural regulation: rethinking management of hypermobility and CNS disorders.

Front Neurol

December 2024

Neuromuscular Imaging Research Lab, The Kolling Institute, North Sydney Local Health District, St Leonards, NSW, Australia.

Individuals with joint hypermobility and the Ehlers-Danlos Syndromes (EDS) are disproportionately affected by neuraxial dysfunction and Central Nervous System (CNS) disorders: such as Spontaneous Intracranial Hypotension (SIH) due to spinal cerebrospinal fluid (CSF) leaks, Upper Cervical Instability (UCI; including craniocervical or atlantoaxial instability (CCI/AAI)), Occult Tethered Cord Syndrome (TCS), Chiari Malformation (CM) and Idiopathic Intracranial Hypertension (IIH). The neuraxis comprises the parts of the nervous system (brain, nerves, spinal cord) along the craniospinal axis of the body. Neuraxial tissue includes all tissue structures that comprise, support, sheath, and connect along the neuraxis and peripheral nerves.

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Torticollis in incomplete Kawasaki disease: a case of atlantoaxial rotatory fixation.

BJR Case Rep

November 2024

Department of Orthopaedic Surgery, Tokyo Metropolitan Toshima Hospital, Tokyo 173-0015, Japan.

Various respiratory, musculoskeletal, gastrointestinal, neurological, and urinary complications have been reported in Kawasaki disease. Here, we describe a rare case of atlantoaxial rotatory fixation (AARF) associated with incomplete Kawasaki disease. The case is of a healthy 4-year-old Japanese boy who had a high-grade fever, lymphadenopathy, and torticollis diagnosed with incomplete Kawasaki disease.

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An eight-year-old female presenting with posterior neck pain and torticollis who had been diagnosed with coronavirus disease 2019 (COVID-19) three weeks earlier was radiographed and diagnosed with atlantoaxial rotatory fixation (AARF). Following treatment with non-steroidal anti-inflammatory drugs (NSAIDs), the posterior neck pain improved, and the torticollis was cured. Symptoms returned after two weeks, and computed tomography showed a 3.

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Article Synopsis
  • - The study evaluates 374 cases of cervical radiculopathy/myelopathy linked to spinal degeneration, particularly focusing on spinal instability as a key factor in treatment.
  • - All patients underwent a specific surgical stabilization technique without decompression procedures, primarily for arthrodesis of the affected cervical segments.
  • - Follow-up results showed significant clinical improvement, especially in patients with severe myelopathy, with many regaining the ability to walk unassisted and no major repeat surgeries needed.
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