Role playing is a central, but underappreciated, process in human evolution. It is a feature not only of the theatrical arts, but of everyday social interactions. While some role playing is limited to enacting various personas of the self (e.g., wife, accountant, mother), others involve an impersonation of people. The most basic form of impersonation is proto-acting, which refers to a transient engagement in character portrayal, such as when we quote a friend during a conversation. During proto-acting, we "act as" some other person. However, there are other means of acting in a similar manner to another person in which we do not impersonate them, but merely their behavior. This might happen when we learn a motor skill from a teacher or conform to the consumer choices of the masses. This follower-based process of "acting like" is a critically important mechanism in cultural evolution since it leads to social conformity and the homogenization of group behavior. I argue that the evolutionary transition from "acting like" (emulation) to "acting as" (impersonation) occurred via the emergence of pantomime and its narrative depiction of the actions of other people. This was probably the first step toward impersonating someone, leading initially to proto-acting and later to theatrical performance in human cultures. Overall, the study of human evolution needs to give greater consideration to role playing and its diverse manifestations in life and art.
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http://dx.doi.org/10.3389/fpsyg.2024.1459247 | DOI Listing |
Histochem Cell Biol
January 2025
Department of Histology and Embryology, Faculty of Medicine, Ankara Yildirim Beyazit University, 06800, Ankara, Turkey.
Bone marrow mesenchymal stromal cells (BM-MSCs) are integral components of the bone marrow microenvironment, playing a crucial role in supporting hematopoiesis. Recent studies have investigated the potential involvement of BM-MSCs in the pathophysiology of acute lymphoblastic leukemia (ALL). However, the exact contribution of BM-MSCs to leukemia progression remains unclear because of conflicting findings and limited characterization.
View Article and Find Full Text PDFJ Biomed Mater Res A
January 2025
Department of Orthopedics, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Bone defects are difficult to treat clinically and most often require bone grafting for repair. However, the source of autograft bone is limited, and allograft bone carries the risk of disease transmission and immune rejection. As tissue engineering technology advances, bone replacement materials are playing an increasingly important role in the treatment of bone defects.
View Article and Find Full Text PDFFASEB J
January 2025
August Krogh Section for Human and Molecular Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
The kinases AMPK, and mTOR as part of either mTORC1 or mTORC2, are major orchestrators of cellular growth and metabolism. Phosphorylation of mTOR Ser1261 is reportedly stimulated by both insulin and AMPK activation and a regulator of both mTORC1 and mTORC2 activity. Intrigued by the possibilities that Ser1261 might be a convergence point between insulin and AMPK signaling in skeletal muscle, we investigated the regulation and function of this site using a combination of human exercise, transgenic mouse, and cell culture models.
View Article and Find Full Text PDFCureus
December 2024
Anesthesiology, Centro Hospitalar Universitário de São João, Porto, PRT.
Background Lung resection is a complex surgical procedure performed in children to address various pulmonary conditions. The success of this surgical intervention in these patients lies in a multidisciplinary approach, with anesthetic management playing a critical role in ensuring the safety and efficacy of the procedure. Methods After approval by the local ethics committee, clinical data of 17 pediatric patients who underwent lung resection in our hospital from January 2012 to December 2022 were retrospectively analyzed.
View Article and Find Full Text PDFFront Psychol
January 2025
Department of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada.
Role playing is a central, but underappreciated, process in human evolution. It is a feature not only of the theatrical arts, but of everyday social interactions. While some role playing is limited to enacting various personas of the self (e.
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