Rationale: Percutaneous endoscopic transforaminal lumbar interbody fusion (PE-TLIF) is a minimally invasive surgical approach for the treatment of lumbar degenerative diseases, Due to the high incidence of surgical complications and long operative time, the cases reported in previous literature were focused on single segment lumbar degenerative diseases. In our study, we present 2 patients who had continuous double-level lumbar degenerated disease.
Patient Concerns: A 71-year-old man with severe low back pain and right leg pain for 3 months, a 57-year-old woman with severe low back pain and bilateral leg pain for 6 months. Conservative treatment is ineffective for both of them.
Diagnoses: Magnetic resonance imaging and physical examination show that the patients had 2 consecutive segments lumbar degenerated disease that required surgical treatment.
Interventions: Considering the poor efficacy of conservative treatment, We performed PE-TLIF on 2 patients.
Outcomes: Finally, both of 2 patients obtained a satisfactory short-term clinical efficacy, without any complications.What's more, the most crucial thing is that average operative time is only 205 minutes.
Lessons: The patients of continuous double-level lumbar degenerated disease treated with PE-TLIF may provide significant support in selecting the appropriate treatments for similar cases and increase the surgical indications for PE-TLIF.
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http://dx.doi.org/10.1097/MD.0000000000041285 | DOI Listing |
J Nurs Res
January 2025
Department of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Background: Population aging has led to a surge in elderly care needs worldwide. Bone aging, skeletal muscle degeneration, and osteoporosis pose critical health challenges for the elderly. The process of bone and skeletal muscle aging not only impacts the functional abilities but also increases fragility fracture risk.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Orthopedic Surgery, Beijing Chaoyang Hospital, Capital Medical University of China, Gongti South Rd, No. 8, Beijing, 100020, China.
Objective: This study aims to investigate changes in matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) levels in the intervertebral discs of New Zealand white rabbits under simulated overload and microgravity conditions, focusing on the expression of MMP1, MMP3, and TIMP1. The findings aim to provide a theoretical foundation for preventing and delaying lumbar disc degeneration in these environments.
Methods: Overload was simulated using an animal centrifuge, and microgravity was mimicked through tail suspension.
Medicine (Baltimore)
January 2025
Ningbo Medical Center LiHuiLi Hospital, Ningbo, Zhejiang, PR China.
Rationale: Alkaptonuria (AKU) is a rare, inherited metabolic disease caused by deficient activity of homogentisic acid oxidase, leading to the accumulation of homogentisic acid and its oxidized product, benzoquinone acetic acid. These compounds cause black discoloration of cartilage, degeneration, inflammation, and calcification of intervertebral disks and large joints, resulting in pain and impaired quality of life. Despite its debilitating effects, there are no curative treatments for AKU, and management remains supportive.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Department of Orthopaedic Surgery, Medical College, Yangzhou University, Yangzhou, China.
Rationale: Percutaneous endoscopic transforaminal lumbar interbody fusion (PE-TLIF) is a minimally invasive surgical approach for the treatment of lumbar degenerative diseases, Due to the high incidence of surgical complications and long operative time, the cases reported in previous literature were focused on single segment lumbar degenerative diseases. In our study, we present 2 patients who had continuous double-level lumbar degenerated disease.
Patient Concerns: A 71-year-old man with severe low back pain and right leg pain for 3 months, a 57-year-old woman with severe low back pain and bilateral leg pain for 6 months.
Integr Med (Encinitas)
December 2024
Borandi Acupuncture, Saint George, UT.
Introduction: Chronic low back pain (CLBP), or low back pain lasting greater than 12 weeks, is a prevalent condition that profoundly impacts the quality of life in affected individuals. Traditional treatments - such as physical therapy, medications, injections, minimally invasive procedures, and surgery - often prove ineffective in a considerable number of cases, particularly when utilized as singular modalities. Given the complex biopsychosocial nature of CLBP, a multi-modality approach tailored to each patients' unique needs is essential.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!