Objective: Systematic review of literature on the pre-clinical studies of dental implantation in different models by finding out data about primary stability.
Materials And Methods: PubMed, NCBI, Wiley Online Library, MBPI, Elibrary systems were used for search.
Results: Based on the literature review of the described animal species dogs have the most similar bone structure to humans but their usage is complicated by ethics and law reasons. They are next followed by rabbits with a frequency of use of 35%. Small ruminants', pigs' and mini-pigs' bones are close to human bones and their use is not ethically complicated. The mini-pig model allows assessing bone and soft tissue status of the previously surgical treated area for a sufficient time. Polyurethane blocks have been proposed as an artificial substitute for in vitro simulation in dental implant placement. The advantage of this material is its homogeneous structure.
Conclusion: Small ruminants, pigs and mini-pigs are the most optimal for preclinical studies on dental implantation.
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