The Study Aims: To evaluate and compare the growth of gingiva around dental implants following the use of collagen matrices and connective tissue grafts (CTG).
Materials And Methods: The study included 80 study participants, who were divided into four groups based on the type of material used to enhance gingival thickness. Two groups utilized collagen matrices, Fibro-Gide and FibroMatrix as materials, while the other two groups utilized CTG obtained from the hard palate or tubercle area of the maxilla as controls. Measurements of gum tissue thickness were obtained before surgery and three- and six-months following surgery using three different methods: mucosa piercing with a spreader and ruler, digital impression, and comparison of cone-beam computed tomography (CBCT) scans and digital impressions.
Results: At six-months examination after the use of grafts from the palate and tubercle, there was a significantly greater increase in gum tissue thickness compared to the use of collagen matrices. The increase was 1.6±0.3 mm and 1.7±0.6 mm for palatal and tubercle grafts, correspondingly, compared to 1.3±0.4 mm for Fibro-Gide and 0.9±0.5 mm for FibroMatrix.
Conclusion: To increase the thickness of soft tissue it is recommended to use CTG from the tubercle or palate. If there is a lack of available donor areas, collagen matrices may be used as a substitute.
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http://dx.doi.org/10.17116/stomat202410306229 | DOI Listing |
The Study Aims: To evaluate and compare the growth of gingiva around dental implants following the use of collagen matrices and connective tissue grafts (CTG).
Materials And Methods: The study included 80 study participants, who were divided into four groups based on the type of material used to enhance gingival thickness. Two groups utilized collagen matrices, Fibro-Gide and FibroMatrix as materials, while the other two groups utilized CTG obtained from the hard palate or tubercle area of the maxilla as controls.
Front Immunol
January 2025
Immunology Translational Research Programme, Yong Loo Lin School of Medicine, Department of Microbiology & Immunology, National University of Singapore, Singapore, Singapore.
Introduction: Collagen is essential for maintaining lung structure and function and its remodeling has been associated with respiratory diseases including chronic obstructive pulmonary disease (COPD). However, the cellular mechanisms driving collagen remodeling and the functional implications of this process in the pathophysiology of pulmonary diseases remain poorly understood.
Methods: To address this question, we employed ; mice with specific depletion of Lyve-1 macrophages and assessed the content, types and organization of collagen in lung compartments at steady state and after chronic exposure to cigarette smoke (CS).
J Anat
January 2025
Bonn Institute of Organismal Biology, Paleontology, University of Bonn, Bonn, Germany.
Current understanding of the histology of the dermoskeleton of tetrapods comes from fossilized and recent remains of skulls, osteoderms, carapace, plastron and other postcranial material which were always investigated using linear cross polarized light (LCPL) microscopy. The pectoral girdle of vast majority of non-amniote tetrapods, including temnospondyls evolved large ventrally located dermal bones- the interclavicle and a pair of clavicles. Despite that, there is a lack of information about the bone tissue structure from these postcranial dermal bones.
View Article and Find Full Text PDFJ Stomatol Oral Maxillofac Surg
January 2025
Department of Oral Surgery, Faculty of Dental Medicine, Saint-Joseph University of Beirut, Beirut, Lebanon. Electronic address:
Soft tissue deficiency around dental implants can negatively impact outcomes in terms of esthetics and long-term stability. While autogenous connective tissue grafting is still considered the gold standard treatment, alternative approaches are being proposed primarily to enhance patient comfort and avoid invasive procedures such as two-sites surgeries using xenogeneic collagen matrices. Despite the advantages, the quality of the regenerated tissues remains unpredictable and, in many cases, questionable, highlighting the need for alternative and innovative approaches.
View Article and Find Full Text PDFACS Biomater Sci Eng
January 2025
Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of liver conditions, ranging from hepatic steatosis to steatohepatitis, fibrosis, and severe outcomes such as cirrhosis or cancer. The progression from hepatic steatosis to fibrosis involves significant extracellular matrix (ECM) remodeling, characterized by increased collagen deposition and cross-linking of ECM proteins, causing increased tissue stiffness and altered MMP expression patterns. Dysregulated MMP expression and extracellular acidosis are key contributors to NAFLD progression.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!