Prurigo Pigmentosa is a rare inflammatory skin disease of unknown origin, characterized by pruritic, erythematous papules on the chest, back, neck, and anterior abdomen. The eruption resolves with reticular hyperpigmentation that cosmetically affects the patient's quality of life. Previous reports highlighted the role of the Ketogenic diet in triggering the disease in young female patients, however, no study reported the occurrence of Prurigo Pigmentosa in siblings of one family, unrelated to a ketogenic diet. Here, we report two sisters diagnosed with Prurigo Pigmentosa without undergoing a Ketogenic diet.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11738638PMC
http://dx.doi.org/10.1002/ccr3.70121DOI Listing

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Prurigo Pigmentosa is a rare inflammatory skin disease of unknown origin, characterized by pruritic, erythematous papules on the chest, back, neck, and anterior abdomen. The eruption resolves with reticular hyperpigmentation that cosmetically affects the patient's quality of life. Previous reports highlighted the role of the Ketogenic diet in triggering the disease in young female patients, however, no study reported the occurrence of Prurigo Pigmentosa in siblings of one family, unrelated to a ketogenic diet.

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Tetracyclines Revisited: Tetracyclines in the Field of Dermatology.

Dermatology

December 2024

Department of Dermatology, Incheon St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.

Article Synopsis
  • * The review discusses various conditions such as hidradenitis suppurativa, vitiligo, and atopic dermatitis, highlighting the diverse applications of tetracyclines in dermatology.
  • * It also examines sarecycline, a new narrow-spectrum tetracycline, emphasizing its clinical effectiveness and potential effects on the microbiome, advocating for a broader use of tetracyclines in treating skin disorders.
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Article Synopsis
  • * A skin biopsy showed mild spongiosis and inflammation, confirming the diagnosis of PP.
  • * Treatment involved stopping the ketogenic diet and using oral doxycycline, which cleared the lesions within a month, although some post-inflammatory hyperpigmentation remained.
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