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| http://dx.doi.org/10.3389/fnhum.2024.1496153 | DOI Listing |
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Investigation of causal associations between cerebral cortical structure and Barrett's esophagus: insights from Mendelian randomization and meta-analysis.
J Thorac Dis
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Surgical Department, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Background: Barrett's esophagus (BE) is a precancerous condition often associated with esophageal adenocarcinoma, influenced by both genetic and environmental factors. However, there is controversy regarding the causal relationship between cerebral cortical structures and BE, with recent studies suggesting a potential neurobiological component to its multifactorial etiology. This study aims to clarify this relationship by utilizing Mendelian randomization (MR) analysis to investigate the potential causal effects of cortical structure variations on BE risk.
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Pharmacological profiling of small molecule modulators of the TMEM16A channel and their implications for the control of artery and capillary function.
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Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA.
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