Insulinoma is a pancreatic neuroendocrine tumour that primarily leads to episodes of hypoglycaemia due to inappropriate and excessive secretion of insulin. It classically presents with neuroglycopenic and autonomic sympathetic symptoms, which resolve promptly with glucose administration. Elevated level of insulin and Cpeptide in the presence of low plasma glucose level and absence of plasma sulfonylurea are diagnostic features. Localisation of the tumour is essential before surgery. However, Insulinoma is difficult to diagnose due to its ambiguous location and insidious course. This is the case of a young male who had 6 months history of adrenergic and neuroglycopenic symptoms, including one episode of seizure. His symptoms resolved with the consumption of high glycaemic indexed food. Biochemical tests were suggestive of insulinoma, but non-invasive imaging techniques including computer tomography (CT) and magnetic resonance imaging (MRI) could not localise the tumour. In this case, pancreatic insulinoma was localised by endoscopic pancreatic ultrasound (EUS). He underwent successful resection of the tumour and his symptoms resolved completely post-surgery.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.47391/JPMA.11001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Coexisting sellar Rathke cleft cyst and planum sphenoidale meningioma: illustrative case.
J Neurosurg Case Lessons
January 2025
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Background: The co-occurrence of Rathke cleft cysts (RCCs) and meningiomas in the sellar and parasellar regions represents an exceedingly rare clinical entity. Achieving maximal resection through a single operative approach while minimizing adverse events is challenging, often necessitating multiple surgical approaches, as suggested by previous reports.
Observations: The authors report the case of a 49-year-old female with a history of kidney transplant who presented with headaches and was diagnosed with coexisting RCC and meningioma in the sellar and planum sphenoidale regions, respectively.
Objective: Evaluation of the effectiveness of vestibuloplasty according to microhemodynamics and oxygenation in the mucous membrane of the alveolar ridge.
Materials And Methods: To achieve this goal, a clinical and functional study was carried out in the mucous membrane of the alveolar ridge after vestibuloplasty in 80 patients (35 men and 45 women) aged from 18 to 65 years, average age 41.5±1.
The long-term success of cardiovascular surgery in Takayasu arteritis: 48 years of experience in Mexico, beyond forefront techniques.
J Thorac Dis
December 2024
Department of Cardiothoracic Surgery, Instituto Nacional de Cardiologia Ignacio Chávez, Mexico City, Mexico.
Background: Takayasu arteritis (TA) affects medium and large caliber arteries causing stenosis, occlusion, or aneurysms. It has great predilection for the aortic arch, subclavian and extracranial arteries. The global prevalence is of 1% to 2% per million inhabitants, which varies by geographical region.
View Article and Find Full Text PDFPeriorbital necrobiotic xanthogranuloma resolved with three years of systemic lenalidomide treatment.
Am J Ophthalmol Case Rep
March 2025
Ophthalmic Surgeons and Consultants of Ohio, Columbus, OH, USA.
Purpose: To describe a case report of the successful management of necrobiotic xanthogranuloma (NXG), a rare periorbital disease.
Observations: A 61-year-old patient presented with bilateral upper and lower lid lesions which were initially misdiagnosed as xanthelasmas and later confirmed to be NXG. Further investigation also uncovered a diagnosis of multiple myeloma.
The epidemiology of cervical cancer among indigenous women living in Latin America: A systematic review.
Prev Med Rep
January 2025
Department of Obstetrics and Gynecology, University of Campinas. Rua Vital Brasil, 80. CEP 13083-888, Campinas, São Paulo, Brazil.
Objective: To review the epidemiological evidence of cervical cancer among Indigenous women living in Latin America.
Methods: We conducted a systematic review of the evidence contained in 10 databases spanning 2003-2019. Two reviewers independently compared papers' titles and abstracts against the inclusionary criteria, and a third reviewer resolved discrepancies.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!