Recent developments and applications of solid membrane in chiral separation.

J Chromatogr A

Shanghai Engineering Research Center of Organ Repair, Joint International Research Laboratory of Biomaterials and Biotechnology in Organ Repair (Ministry of Education), School of Medicine, Shanghai University, Shanghai 200444, China; Shanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China. Electronic address:

Published: January 2025

Chirality is a fundamental property in nature, and chiral molecules are closely related to human health and the origin of life. Therefore, the exploration and preparation of optically active compounds of paramount importance. Membrane separation is a large-scale and continuous separation technique that has been developing quickly in recent years. It has many potential applications, particularly in chiral membrane separation technology, which is currently a hotspot for study. Depending on the types of membranes, chiral membranes can be divided into two categories: chiral solid membranes and chiral liquid membranes. Solid membranes outperform the others in terms of better mechanical performance and separation efficiency. This review presents in-depth summaries of chiral solid membranes made of different materials, and their applications in drug separation. It also providing insights into the potential for the future development of chiral solid membranes.

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Source
http://dx.doi.org/10.1016/j.chroma.2025.465652DOI Listing

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