Background: This study aimed to create a comprehensive Core Outcome Set (COS) for assessing the long-term outcome (≥ 5 years) after Metabolic Bariatric Surgery (MBS), through the use of the Delphi method.
Methods: The study utilized a three-phase approach. In Phase 1, a long list of items was identified through a literature review and expert input, forming the basis for an online Delphi survey. In Phase 2, Dutch healthcare professionals involved in MBS care, defined as having at least 1 year of experience in routine follow-up or managing issues arising during follow-up, rated the importance of these items over three Delphi rounds using a 5-point Likert scale. Participants had the option to suggest additional items. Consensus was defined as 75% agreement among panelists. In Phase 3, the final COS was validated at a national conference.
Results: Thirty-one professionals participated in the first Delphi round. Of these, 28 (90%) completed the second round, and 24 (77%) completed the third round. The final COS, validated by 18 healthcare professionals, included various domains: short-term textbook outcome, weight loss, remission of comorbidities, quality of life, micronutrient deficiencies, lifestyle, psychopathology, long-term complications, and preoperative indication.
Conclusions: The final COS offers a multidimensional approach to evaluate long-term outcomes after MBS. This COS is expected to enhance the measurement and benchmarking of MBS care, providing a more holistic view of patient outcomes.
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http://dx.doi.org/10.1007/s11695-024-07587-6 | DOI Listing |
Obes Surg
January 2025
Ziekenhuis Groep Twente, Almelo, Netherlands.
Background: This study aimed to create a comprehensive Core Outcome Set (COS) for assessing the long-term outcome (≥ 5 years) after Metabolic Bariatric Surgery (MBS), through the use of the Delphi method.
Methods: The study utilized a three-phase approach. In Phase 1, a long list of items was identified through a literature review and expert input, forming the basis for an online Delphi survey.
AAPS PharmSciTech
January 2025
Department of Pharmaceutics, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Dakahlia, Egypt.
Lung inflammation is a hallmark of several respiratory diseases. Despite the great effectiveness of the synthetic antiinflammatory agents, they cause potential side effects. Polydatin (PD), a natural phytomedicine, has antioxidant and antiinflammatory effects.
View Article and Find Full Text PDFEur J Pain
February 2025
Department of Research, Sint Maartenskliniek, Nijmegen, The Netherlands.
Background: After lumbar spine surgery, a Core Outcome Set (COS) for acute pain is essential to ensure that the most meaningful outcomes are monitored consistently in the perioperative period. The aim of the present study was to consent on a COS for assessing the efficacy of acute pain management for patients undergoing lumbar spinal surgery.
Method: A modified Delphi procedure was conducted among a national (Dutch) expert panel.
BMJ Open
January 2025
Department of Pediatric Surgery, Emma Children's Hospital, Amsterdam UMC, Amsterdam, Noord-Holland, The Netherlands.
Introduction: There is a lack of consensus on the optimal surgical strategy for differentiated thyroid cancer (DTC), partly due to inconsistent reporting of outcomes. This limits the ability to compare study results, hindering the ability to draw conclusions regarding novel treatment strategies. The development of a core outcome set (COS) reduces heterogeneity in the selection and reporting of clinical trial outcomes.
View Article and Find Full Text PDFTrials
January 2025
Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Background: Leptospirosis is a zoonotic bacterial infection occurring worldwide. It is of particular public health concern due to its global distribution, epidemic potential and high mortality without appropriate treatment. The method for the management of leptospirosis, particularly in severe disease, is clouded by methodological inconsistency and a lack of standardized outcome measures.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!