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The Farrington Curve: A Commentary on How David Farrington Showed How to Prioritise the Most Harmful Offenders.
Crim Behav Ment Health
January 2025
Institute of Criminology, University of Cambridge, Cambridge, UK.
Different Pathways of Externalising Behaviour Problems From Preschool to Youth: A Test of Risk and Protective Factors and Potential Origins.
Crim Behav Ment Health
January 2025
Institute of Psychology, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
Background: This article is dedicated to David Farrington who was a giant in criminology and, in particular, a pioneer in studying developmental pathways of delinquent and antisocial behaviour. Numerous studies followed his work. Systematic reviews of his and others' research described between two and seven (mainly 3-5) trajectories.
View Article and Find Full Text PDFNeuropsychiatric symptoms in cognitive decline and Alzheimer's disease: biomarker discovery using plasma proteomics.
J Neurol Neurosurg Psychiatry
September 2024
Department of Psychiatry, Psychotherapy and Psychosomatics, University of Zurich, Psychiatric University Hospital, Zurich, Switzerland
Background And Objectives: Neuropsychiatric symptoms (NPS) are common in older people with cognitive impairment and Alzheimer's disease (AD). No biomarkers to detect the related pathology or predict the clinical evolution of NPS are available yet. This study aimed to identify plasma proteins that may serve as biomarkers for NPS and NPS-related clinical disease progression.
View Article and Find Full Text PDFDevelopment and Validation of Risk Prediction Models for Colorectal Cancer in Patients with Symptoms.
J Pers Med
June 2023
Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh EH8 9AG, UK.
We aimed to develop and validate prediction models incorporating demographics, clinical features, and a weighted genetic risk score (wGRS) for individual prediction of colorectal cancer (CRC) risk in patients with gastroenterological symptoms. Prediction models were developed with internal validation [CRC Cases: n = 1686/Controls: n = 963]. Candidate predictors included age, sex, BMI, wGRS, family history, and symptoms (changes in bowel habits, rectal bleeding, weight loss, anaemia, abdominal pain).
View Article and Find Full Text PDFPreoperative left shoulder elevation > 1 cm is predictive of severe postoperative shoulder imbalance in early onset idiopathic scoliosis patients treated with growth-friendly instrumentation.
Spine Deform
September 2023
Department of Orthopaedic Surgery, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Purpose: Prior research has demonstrated the influence of preoperative shoulder elevation (SE), proximal thoracic curve magnitude, and upper instrumented vertebra (UIV) on shoulder balance after PSF for AIS. Our purpose was to evaluate the impact of these factors on shoulder balance in early onset idiopathic scoliosis (EOIS) patients treated with growth-friendly instrumentation.
Methods: This was a multicenter retrospective review.
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