Polyphenols as a strategy for improving male reproductive system.

Mol Biol Rep

Center for Environmental and Human Toxicology, Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.

Published: January 2025

Reproduction in males is one of the complicated processes that is mediated by many environmental factors, as well as by diet (e.g. supplements, nutritional value). The parameters of reproduction like sperm cells, hormones and testicular histology are highly prone to oxidative stress due to influence of factors on reproductive processes. Polyphenols are naturally present in feed of animals as shrubs, trees and agro-industrial by products. The exposures of these polyphenols through diet have strong antioxidants properties. However, the benefits of these substances on reproductive health are not always certain. The use of these polyphenols in the diet of animals and in the semen extender has been reported as remarkable benefits. These beneficial effects are manifested in the form of improvement of antioxidant potential via the reduction in the production of reactive oxygen species. Polyphenols are also used for cryopreservation of various species for the genetic improvement of various species. This review gathers all the findings related to dietary consumptions of polyphenols on reproductive performance of male of various species as well as use in semen extender in fresh and frozen semen.

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http://dx.doi.org/10.1007/s11033-025-10240-9DOI Listing

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