Background Patient safety incident reporting and analysis are often confined to secondary care, despite 95% of dentistry occurring in primary care. Peninsula Dental Social Enterprise (PDSE) delivers primary care dentistry in education-based settings and uses a report-review-action process to underpin its patient safety framework.Aim This article analyses trends in clinical incident data, reflecting on learning to improve overall patient safety.Methods A retrospective observational study was employed to analyse incidents over a five-year period (2017-2022) using anonymised data from the PDSE reporting system.Results Over the five-year reporting period, there were an average of 13.1 total incidents per 1,000 appointments. Sub-analysis of reported incidents revealed 1.5 clinical incidents and 0.9 'near miss' incidents. A soft-tissue injury rate of 0.6, a contamination injury rate of 0.9, and 0.3 written complaints were reported per 1,000 appointments.Conclusion Patient safety is a key component of quality dental care, especially when delivering clinical dental education. PDSE fosters an environment of transparency, enabling the provider to monitor incidents and learn from them. This results in systems improvements sitting at the heart of the clinical service. With a lack of data published from similar settings, comparison to the sector is limited. Further sharing of data is encouraged to enable standardisation and quality benchmarking.
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http://dx.doi.org/10.1038/s41415-024-7952-0 | DOI Listing |
Thromb J
January 2025
College of Pharmacy, QU Health, Qatar University, Doha, Qatar.
Background: Nephrotic syndrome (NS) is associated with an increased risk of venous thromboembolism (VTE). Anticoagulants are widely used in the prevention of VTE in NS patients. The use of direct oral anticoagulants (DOACs) has not been studied intensively in NS patients.
View Article and Find Full Text PDFBMC Med Educ
January 2025
Health Professions Education Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
Background: Educational research highlights active approaches to learning are more effective in knowledge retention and problem-solving. It has long been acknowledged that adapting to more active ways of learning form part of the challenge for new university students as the pedagogical distance between the didactical approach largely followed by secondary school systems the world over differs quite significantly from the often more student-led, critical approach taken by universities. University students encounter various learning challenges, particularly during the transition from secondary school to university.
View Article and Find Full Text PDFJ Feline Med Surg
January 2025
Independent Biostatistics Consultant, Denver, CO, USA.
Objectives: The objective of this study was to evaluate the impact of liposomal bupivacaine (LB) as part of an opioid-sparing multimodal analgesic protocol on postoperative pain control in cats undergoing limb amputation surgery compared with traditional pain management protocols more heavily reliant on injectable opioid and non-opioid analgesics.
Methods: Medical records of 29 cats that underwent forelimb or hindlimb amputation were reviewed to evaluate postoperative systemic pain medications utilized, appetite and time to discharge as presumptive gauges of postoperative pain. Statistical analysis of the data included Wilcoxon's rank-sum test and Fisher's exact test.
NPJ Vaccines
January 2025
Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK.
The rapid development and worldwide distribution of COVID-19 vaccines is a remarkable achievement of biomedical research and logistical implementation. However, these developments are associated with the risk of a surge of substandard and falsified (SF) vaccines, as illustrated by the 184 incidents with SF and diverted COVID-19 vaccines which have been reported during the pandemic in 48 countries, with a paucity of methods for their detection in supply chains. In this context, matrix-assisted laser desorption ionisation-time of flight (MALDI-ToF) mass spectrometry (MS) is globally available for fast and accurate analysis of bacteria in patient samples, offering a potentially accessible solution to identify SF vaccines.
View Article and Find Full Text PDFAMB Express
January 2025
Department of Respiratory and Critical Care, Haining Branch, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Cryptococcal pneumonia is a severe fungal infection of the respiratory system, predominantly caused by Cryptococcus neoformans. Its incidence is increasing, driven by evolving pathogen dynamics and heightened susceptibility among patient populations. This investigation aimed to assess the combined therapeutic efficacy of Fluconazole and Amphotericin B for cryptococcal pneumonia and to explore the roles of miR-15b and TGF-β1 in modulating treatment response.
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