Background: Older adults with mild behavioral impairment (MBI) are at the higher risk of developing dementia compared to those without MBI, leading to decreased quality of life (QoL). Addressing MBI in older adults provides valuable opportunities to prevent dementia.
Objectives: This study aimed to determine the effects of traditional Thai folk dance combined with a cognitive stimulation program on MBI, QoL, subjective cognitive decline (SCD), and cognitive functioning in older Thai adults.
Design: Single-blinded, two-armed, randomized controlled trial, with a three-month follow-up period.
Setting: Outpatient chronic disease clinics at two districts in Suphan Buri province, Thailand.
Participants: One-hundred twenty-eight older adults with MBI were randomly assigned to either the experimental (n = 64) and cognitive education control group (n = 64).
Intervention: The 14-session, 7-week traditional Thai folk-dance program combined with cognitive stimulation focused on enhanced moderate intensity physical activity and cognitive stimulation engagement to improve MBI of older adults.
Measurements: The primary outcome was MBI assessed using Mild Behavioral Impairment Checklist. Secondary outcomes were QoL, SCD, and cognitive tests of memory and executive functions.
Results: Compared to the control group, participants in the experimental group demonstrated significantly reduced MBI (p <.01), improved QoL (p <.01), decreased SCD (p <.01), and enhanced cognitive functioning (p <.01) after the 7-week intervention and at the 12-week follow-up.
Conclusion: The traditional Thai folk dance combined with cognitive stimulation improved outcomes related to early signs of dementia and enhanced the overall QoL of older adults.
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http://dx.doi.org/10.1016/j.tjpad.2025.100066 | DOI Listing |
iScience
January 2025
Laboratory for Neuroengineering, Department of Health Science and Technology, Institute for Robotics and Intelligent Systems, ETH Zürich, 8092 Zürich, Switzerland.
Our brain combines sensory inputs to create a univocal perception, enhanced when stimuli originate from the same location. Following amputation, distorted body representations may disrupt visuo-tactile integration at the amputated leg. We aim to unveil the principles guiding optimal and cognitive-efficient visuo-tactile integration at both intact and amputated legs.
View Article and Find Full Text PDFNeural Regen Res
January 2025
Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, OH, USA.
Adult neurogenesis continuously produces new neurons critical for cognitive plasticity in adult rodents. While it is known transforming growth factor-β signaling is important in embryonic neurogenesis, its role in postnatal neurogenesis remains unclear. In this study, to define the precise role of transforming growth factor-β signaling in postnatal neurogenesis at distinct stages of the neurogenic cascade both in vitro and in vivo, we developed two novel inducible and cell type-specific mouse models to specifically silence transforming growth factor-β signaling in neural stem cells in (mGFAPcre-ALK5fl/fl-Ai9) or immature neuroblasts in (DCXcreERT2-ALK5fl/fl-Ai9).
View Article and Find Full Text PDFJ Psychiatr Res
January 2025
Department of Psychiatry and Clinical Psychology, Clínica Universidad de Navarra, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain.
The detection of rare or deviant stimuli shares common brain circuits involved in temporal processing and salience, critical for cognitive control. Disruption in these processes may contribute to the mechanisms of the disease and explain cognitive deficits observed in psychosis and related disorders. We designed a neuroimaging study, using oddball task-based functional sequences (fMRI) and diffusion tensor imaging (DTI), comparing healthy controls (HC, n = 14, 7 females) and patients with stable psychosis (PSY, n = 20, 10 females).
View Article and Find Full Text PDFJ Neural Eng
January 2025
School of Computer Science and Electronic Engineering, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
Objective Race driving is a complex motor task that involves multiple concurrent cognitive processes in different brain regions coordinated to maintain and optimize speed and control. Delineating the neuroplasticity accompanying the acquisition of complex and fine motor skills such as racing is crucial to elucidate how these are gradually encoded in the brain and inform new training regimes. This study aims, first, to identify the neural correlates of learning to drive a racing car using non-invasive electroencephalography (EEG) imaging and longitudinal monitoring.
View Article and Find Full Text PDFPLoS One
January 2025
School of Communication Sciences & Disorders, University of Memphis, Memphis, Tennessee, United States of America.
We aimed to test whether hearing speech in phonetic categories (as opposed to a continuous/gradient fashion) affords benefits to "cocktail party" speech perception. We measured speech perception performance (recognition, localization, and source monitoring) in a simulated 3D cocktail party environment. We manipulated task difficulty by varying the number of additional maskers presented at other spatial locations in the horizontal soundfield (1-4 talkers) and via forward vs.
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