This study investigated the potential of Maillard reaction products (MRPs) derived from mung bean protein isolate (MBPI) and peach gum (PG) conjugates as wall materials for microencapsulating chia seed oil (CSO). Four formulations (MMRP) were prepared using spray-drying and compared to a commercial sample (CMMRP). The MMRP formulation exhibited the highest encapsulation yield (91 %) and encapsulation efficiency (96 %), along with favorable physical properties, including a spherical shape and smooth surface. All formulation showed significantly greater stability during storage at 4 °C compared to 25 °C. After 30 days of storage, the MMRP formulation exhibited significantly higher oxidative stability, as evidenced by lowest peroxide values (0.3 and 0.24 mEq O/kg CSO at 4 °C and 25 °C, respectively). Furthermore, the MMRP formulation displayed the slowest decrease in DPPH radical scavenging activity, reaching 6.6 % at 4 °C and 10.4 % at 25 °C after 30 days, compared to 14.2 % and 20.9 % for CMMRP samples, correspondingly. Molecular dynamics simulations confirmed the effectiveness of MRPs as encapsulants for CSO. Overall, the results suggest that CSO microencapsulated with MRPs of MBPI-PG can be a valuable addition to various food products for long-term storage.
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http://dx.doi.org/10.1016/j.ijbiomac.2025.139959 | DOI Listing |
Int J Biol Macromol
January 2025
State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, PR China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, PR China. Electronic address:
This study investigated the potential of Maillard reaction products (MRPs) derived from mung bean protein isolate (MBPI) and peach gum (PG) conjugates as wall materials for microencapsulating chia seed oil (CSO). Four formulations (MMRP) were prepared using spray-drying and compared to a commercial sample (CMMRP). The MMRP formulation exhibited the highest encapsulation yield (91 %) and encapsulation efficiency (96 %), along with favorable physical properties, including a spherical shape and smooth surface.
View Article and Find Full Text PDFACS Infect Dis
October 2017
Experimental Chemotherapy Laboratory, VA Medical Center (Mail code RD-33), 3710 SW US Veterans Hospital Road, Portland, Oregon 97239, United States.
ELQ-300 is a preclinical antimalarial drug candidate that is active against liver, blood, and transmission stages of Plasmodium falciparum. While ELQ-300 is highly effective when administered in a low multidose regimen, poor aqueous solubility and high crystallinity have hindered its clinical development. To overcome its challenging physiochemical properties, a number of bioreversible alkoxycarbonate ester prodrugs of ELQ-300 were synthesized.
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