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Dressed Majorana Fermion in a Hybrid Nanowire.
Phys Rev Lett
December 2024
Beijing Computational Science Research Center, Beijing 100193, China.
In hybrid systems where nanowires are proximity-coupled with superconductors, the low-energy theory fails to determine the topological phase with Majorana fermion (MF) when the magnetic field or proximity coupling is much stronger. To overcome this limitation, we propose a holistic approach that defines MF by considering both the motion of electrons in the nanowire and the quasiparticle excitations in the superconductor. This approach transcends the constraints of low-energy theory and offers broad applicability.
View Article and Find Full Text PDFDeveloping and Implementing an Integrated Family Education Program (IPMD-F) for Parents of Children With Reading Difficulties: Insights From an Action Research Study.
Brain Behav
January 2025
Faculty of Health Sciences, Child Development Department, Hacettepe University, Ankara, Turkey.
Purpose: This research aims to identify the problems and needs of families of children with reading difficulties, develop an Integrated Process-Based Family Education Program (IPMD-F) to address these needs, and implement it.
Methods: The study used a community-based participatory action research approach, following a four-stage process: general information collection, needs identification and action plan creation, development and implementation of the IPMD-F, and evaluation. Conducted during the 2023-2024 academic year in Ankara, Turkey, with 16 volunteer parents of children diagnosed with learning disabilities, data were collected using qualitative and quantitative tools.
A Molecular Perspective of Exciton Condensation from Particle-Hole Reduced Density Matrices.
J Phys Chem Lett
January 2025
Department of Chemistry and The James Franck Institute, The University of Chicago, Chicago, Illinois 60637, United States.
Exciton condensation, the Bose-Einstein-like condensation of quasibosonic particle-hole pairs, has been the subject of much theoretical and experimental interest and holds promise for ultraenergy-efficient technologies. Recent advances in bilayer systems, such as transition metal dichalcogenide heterostructures, have brought us closer to the experimental realization of exciton condensation without the need for high magnetic fields. In this perspective, we explore progress toward understanding and realizing exciton condensation, with a particular focus on the characteristic theoretical signature of exciton condensation: an eigenvalue greater than one in the particle-hole reduced density matrix, which signifies off-diagonal long-range order.
View Article and Find Full Text PDFOptimal timing of pharmacoinvasive strategy and its impact on clinical and economic outcomes in patients with ST-elevation myocardial infarction: a real-world perspective.
Front Cardiovasc Med
January 2025
Laboratory of Data for Quality of Care and Outcomes Research (LaDa:QCOR), Catholic University of Brasilia, Brasília, Brazil.
Background: The pharmacoinvasive (PhI) strategy is the standard-of-care for ST-elevation myocardial infarction (STEMI) patients when primary percutaneous coronary intervention (pPCI) is unfeasible. Optimal timing for post-fibrinolytic PCI (lysis-PCI) remains elusive. Therefore, this study aimed to assess the clinical and economic impacts of early vs.
View Article and Find Full Text PDFUnveiling inverted D genes and D-D fusions in human antibody repertoires unlocks novel antibody diversity.
Commun Biol
January 2025
Large Molecules Research, Sanofi, Cambridge, MA, USA.
Antibodies, essential components of adaptive immunity, derive their remarkable diversity primarily from V(D)J gene rearrangements, particularly within the heavy chain complementarity-determining region 3 (CDR-H3) where D genes play a major role. Traditionally, D genes were thought to recombine only in the forward direction, despite having identical recombination signal sequences (12 base pair spacers) at both ends. This observation led us to question whether these symmetrical sequences might enable bidirectional recombination.
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