Significance: Machine learning models for the direct extraction of tissue parameters from hyperspectral images have been extensively researched recently, as they represent a faster alternative to the well-known iterative methods such as inverse Monte Carlo and inverse adding-doubling (IAD).

Aim: We aim to develop a Bayesian neural network model for robust prediction of physiological parameters from hyperspectral images.

Approach: We propose a two-component system for extracting physiological parameters from hyperspectral images. First, our system models the relationship between the measured spectra and the tissue parameters as a distribution rather than a point estimate and is thus able to generate multiple possible solutions. Second, the proposed tissue parameters are then refined using the neural network that approximates the biological tissue model.

Results: The proposed model was tested on simulated and data. It outperformed current models with an overall mean absolute error of 0.0141 and can be used as a faster alternative to the IAD algorithm.

Conclusions: Results suggest that Bayesian neural networks coupled with the approximation of a biological tissue model can be used to reliably and accurately extract tissue properties from hyperspectral images on the fly.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737236PMC
http://dx.doi.org/10.1117/1.JBO.30.1.016004DOI Listing

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