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http://dx.doi.org/10.4103/ajts.ajts_125_23 | DOI Listing |
Asian J Transfus Sci
February 2024
Department of Physiology, Mahatma Gandhi Medical College, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, India.
Int J Mol Sci
April 2024
Centre Borelli, ENS Paris-Saclay, CNRS, Université Paris-Saclay, 4 Avenue des Sciences, 91190 Gif-sur-Yvette, France.
The human Vitamin K Epoxide Reductase Complex (hVKORC1), a key enzyme that converts vitamin K into the form necessary for blood clotting, requires for its activation the reducing equivalents supplied by its redox partner through thiol-disulphide exchange reactions. The functionally related molecular complexes assembled during this process have never been described, except for a proposed de novo model of a 'precursor' complex of hVKORC1 associated with protein disulphide isomerase (PDI). Using numerical approaches ( modelling and molecular dynamics simulation), we generated alternative 3D models for each molecular complex bonded either covalently or non-covalently.
View Article and Find Full Text PDFJCO Oncol Pract
April 2024
Chao Family Comprehensive Cancer Center, Division of Hematology and Oncology, Department of Medicine, University of California, Irvine, Orange, CA.
VideoEndocrinology
September 2023
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Thermal injury to recurrent laryngeal nerve (RLN) during radiofrequency ablation (RFA) can produce temporary or permanent vocal cord paralysis. Hydrodissection with cold 5% glucose of "danger triangle" protects RLN during RFA. When RFA is performed under local anesthesia, RLN function is monitored by patients producing vocal sounds.
View Article and Find Full Text PDFVaccines (Basel)
July 2023
National Reference Laboratory for African Swine Fever, Istituto Zooprofilattico Sperimentale Umbria-Marche "Togo Rosati", 06126 Perugia, Italy.
African swine fever virus (ASFV) is the etiological agent of a haemorrhagic disease that threatens the global pig industry. There is an urgency to develop a safe and efficient vaccine, but the knowledge of the immune-pathogenetic mechanisms behind ASFV infection is still very limited. In this paper, we evaluated the haematological and immunological parameters of domestic pigs vaccinated with the ASFV Lv17/WB/Rie1 strain or its derived mutant Lv17/WB/Rie1/d110-11L and then challenged with virulent Armenia/07 ASFV.
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