Fetal and neonatal cardiac tumors are rare and often benign. Clinical presentation is primarily related to mass effect, pericardial effusion or arrhythmia. Prenatal detection can assist with risk assessment and inform optimal delivery plan and postnatal management. We report a fetus with a right atrial mass discovered in the third trimester. After successful surgical resection, pathology confirmed the mass to be a capillary-venous malformation, which are rare and challenging to diagnose. The true incidence of these vascular malformations within cardiac spaces is difficult to discern given the historic classification of numerous different vascular malformations under the umbrella term hemangioma.
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http://dx.doi.org/10.1016/j.jaccas.2024.102922 | DOI Listing |
JACC Case Rep
December 2024
Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Fetal and neonatal cardiac tumors are rare and often benign. Clinical presentation is primarily related to mass effect, pericardial effusion or arrhythmia. Prenatal detection can assist with risk assessment and inform optimal delivery plan and postnatal management.
View Article and Find Full Text PDFCureus
November 2024
Department of Oral and Maxillofacial Surgery, Meghna Institute of Dental Sciences, Nizamabad, IND.
Vascular malformations (VMs) are congenital abnormalities of blood or lymphatic vessels, present at birth and growing proportionally with the individual. They are classified into types such as capillary, venous, lymphatic, and arteriovenous malformation (AVMs). Symptoms include discoloration, swelling, pain, or functional impairment, depending on the type and location.
View Article and Find Full Text PDFSemin Pediatr Neurol
October 2024
The University of Texas at Austin, Dell Medical School, Department of Neurology, 1601 Trinity St., Bldg. B, Stop Z0700 Austin, TX 78712, USA; Dell Children's Medical Center, 4910 Mueller Blvd Suite 300 Austin, TX 78723, USA. Electronic address:
Signal Transduct Target Ther
June 2024
Université Paris Cité, Paris, France.
Sporadic venous malformations are genetic conditions primarily caused by somatic gain-of-function mutation of PIK3CA or TEK, an endothelial transmembrane receptor signaling through PIK3CA. Venous malformations are associated with pain, bleedings, thrombosis, pulmonary embolism, esthetic deformities and, in severe cases, life-threatening situations. No authorized medical treatment exists for patients with venous malformations.
View Article and Find Full Text PDFJ Invest Dermatol
September 2024
Laboratory of Human Molecular Genetics, de Duve Institute, UCLouvain, Brussels, Belgium; Center for Vascular Anomalies, Division of Plastic Surgery, VASCERN VASCA European Reference Center, Cliniques Universitaires Saint Luc, UCLouvain, Brussels, Belgium; WELBIO Department, WEL Research Institute, Wavre, Belgium. Electronic address:
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