Is germline genome-editing person-affecting or identity-affecting, and does it matter?

Bioethics

Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Published: January 2025

Writers have debated whether germline genome-editing is person-affecting or identity-affecting. The difference is thought to be ethically relevant to whether we should choose genome-editing or choose preimplantation genetic diagnosis and embryo selection, when seeking to prevent or produce bad conditions (e.g., cystic fibrosis, or deafness) in the individuals who will grow from the embryo edited or selected. We consider the very recent views of three prominent bioethicists and philosophers who have grappled with this issue. We claim that both sides are right, but that the sense in which genome-editing is person-affecting is less important, morally, when the aim is to have healthy children. Since this is the predominant objective of engaging in embryo selection and genome-editing, and since there are certain risks, at least for now, with genome-editing, it remains better, morally, to engage in embryo selection than genome-editing.

Download full-text PDF

Source
http://dx.doi.org/10.1111/bioe.13385DOI Listing

Publication Analysis

Top Keywords

genome-editing person-affecting
12
embryo selection
12
germline genome-editing
8
person-affecting identity-affecting
8
selection genome-editing
8
genome-editing
6
identity-affecting matter?
4
matter? writers
4
writers debated
4
debated germline
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!