A Rare Combination of Bleeding Disorders in South Dakota: A Case Report.

Hemophilia A is a clotting disorder due to factor VIII deficiency, leading to prolonged bleeding. Acquired hemophilia A results from the immune system attacking factor VIII, typically occurring later in life. Factor V Leiden is a genetic mutation causing abnormal blood clot formation, primarily in veins. This mutation is inheritable and increases the risk of clotting. A combination of these conditions is extremely rare. Correct management of a patient with any bleeding disorder is imperative for a surgical case to prevent catastrophe. We present a surgical case involving both hemophilia A and Factor V Leiden.