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http://dx.doi.org/10.1038/d41586-025-00148-6DOI Listing

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Article Synopsis
  • Inflammasomes are important protein complexes in the immune system, and their malfunction is connected to various health issues, necessitating targeted treatments based on specific diseases.
  • Researchers developed a sophisticated imaging assay for human immune cells, utilizing machine learning and cell biology techniques to analyze cellular responses related to inflammasome activity.
  • This approach successfully identified over 100 distinct inflammasome inhibitors from a large library of compounds, showcasing the potential for machine learning to enhance the understanding of complex biological processes and aid in drug discovery.
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