Objectives: Urinary incontinence (UI) is prevalent among women, particularly during the postpartum period, impacting various aspects of quality of life (QoL). The objectives of this study are to determine the prevalence of postpartum UI among Palestinian women, explore its relationship with delivery mode, identify associated risk factors and assess its impact on QoL.
Design: A cross-sectional study.
Setting And Participants: The study targeted postpartum women attending primary healthcare centres in the North West Bank of Palestine. Data were collected using interviewer-administered questionnaires. The primary outcome was the prevalence of postpartum UI, and the secondary outcomes included risk factors associated with UI and its impact on QoL. We used multivariate logistic regression analysis to identify factors associated with UI while adjusting for confounding variables. The Institutional Review Board of An-Najah National University approved the study.
Results: Out of 507 participants, 13.6% (95% CI 10.8% to 16.9%) experienced postpartum UI, with 78.3% reporting moderate-to-severe symptoms. Maternal body mass index (BMI) (adjusted OR (aOR) 1.98; 95% CI 1.1 to 3.7; adjusted p=0.033) and experiencing UI during the last pregnancy (aOR 2.25; 95% CI 1.3 to 3.8; adjusted p=0.003) were significant risk factors for postpartum UI. No significant association was found between the normal vaginal delivery and postpartum UI compared with caesarean section (aOR 1.5; 95% CI 0.90 to 1.5; adjusted p=0.284). Postpartum UI severity significantly correlated with QoL, particularly in social embarrassment (p=0.005), psychosocial impact (p≤0.001) and avoidance and limiting behaviours (p≤0.001).
Conclusion: The prevalence of postpartum UI in Palestinian women is consistent with global findings. Experiencing UI during the last pregnancy and higher maternal BMI were identified as key risk factors for postpartum UI. These results highlight the need for early detection, intervention and preventive strategies to mitigate the impact of postpartum UI on QoL.
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http://dx.doi.org/10.1136/bmjopen-2024-087585 | DOI Listing |
JMIR Med Inform
January 2025
Department of Systems Design Engineering, Faculty of Engineering, University of Waterloo, Waterloo, ON, Canada.
Background: While expert optometrists tend to rely on a deep understanding of the disease and intuitive pattern recognition, those with less experience may depend more on extensive data, comparisons, and external guidance. Understanding these variations is important for developing artificial intelligence (AI) systems that can effectively support optometrists with varying degrees of experience and minimize decision inconsistencies.
Objective: The main objective of this study is to identify and analyze the variations in diagnostic decision-making approaches between novice and expert optometrists.
AIDS Care
January 2025
Department of Knowledge Management, Sociedad Integral de Especialistas en Salud (SIES Salud IPS), Bogotá, Colombia.
The most significant progress in addressing the HIV/AIDS epidemic has been the development of antiretroviral therapy (ART). However, ensuring a high degree of treatment adherence is necessary to prevent resistance and disease progression. We conducted a cross-sectional study to evaluate adherence to ART through the calculation of the medication possession ratio (MPR) and to identify risk factors for suboptimal adherence in a cohort of HIV-positive patients receiving care at a Colombian healthcare institution across 16 cities.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland.
Importance: Sensitivity to environmental stress and adversity may influence lung cancer risk, highlighting a critical link between psychosocial factors and cancer etiology.
Objective: To evaluate whether genetically estimated sensitivity to environmental stress and adversity is associated with lung cancer risk.
Design, Setting, And Participants: Data were obtained from a genome-wide association study identifying 37 independent genetic variants strongly associated with sensitivity to environmental stress and adversity and a cross-ancestry genome-wide meta-analysis from the International Lung Cancer Consortium.
J Vis Exp
January 2025
Institute of Biochemistry and Molecular Biology, Hengyang Medical School, University of South China; National Health Commission Key Laboratory of Birth Defect Research and Preventio, Hunan Provincial Maternal and Child Health Care Hospital;
Both DNA replication and RNA transcription utilize genomic DNA as their template, necessitating spatial and temporal separation of these processes. Conflicts between the replication and transcription machinery, termed transcription-replication conflicts (TRCs), pose a considerable risk to genome stability, a critical factor in cancer development. While several factors regulating these collisions have been identified, pinpointing primary causes remains difficult due to limited tools for direct visualization and clear interpretation.
View Article and Find Full Text PDFAging Clin Exp Res
January 2025
Department of Physical Medicine and Rehabilitation, Kansai Medical University, Osaka, Japan.
Background: Falls on stairs are a major cause of severe injuries among older adults, with stair descent posing significantly greater risks than ascent. Variations in stair descent phenotypes may reflect differences in physical function and biomechanical stability, and their identification may prevent falls.
Aims: This study aims to classify stair descent phenotypes in older adults and investigate the biomechanical and physical functional differences between these phenotypes using hierarchical cluster analysis.
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