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Transoral endoscopic thyroid lobectomy and ipsilateral central neck lymph node dissection vestibular approach: analysis of the learning curve and clinical outcomes evaluation.
Front Endocrinol (Lausanne)
January 2025
Department of Thyroid Surgery, Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, China.
Purpose: The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is distinguished by its ability to leave no visible scars on the body's surface. Currently, there is still a lack of single-center large sample size analysis on the learning curve of TOETVA, especially for the treatment of thyroid cancer. This study aims to fill this void by presenting a comprehensive analysis of the learning curve and assessing the procedure's feasibility in managing thyroid cancer.
View Article and Find Full Text PDFThe pattern and burden of non-communicable diseases in armed conflict-exposed populations in Northeastern Nigeria.
PeerJ
January 2025
Department of Nursing and Public Health, University of Northern Iowa, Iowa, United States of America.
Background: The risk of non-communicable diseases (NCDs) in conflict and post-conflict settings in Northeastern Nigeria has not been evaluated to date. As this region undergoes recovery, understanding the prevalence of NCDs, such as hypertension, diabetes, depression, and obesity, and the associated behavioral coping mechanisms, is crucial for developing tailored healthcare solutions. Therefore, this study aimed to assess the impact of conflict on the prevalence of NCDs in conflict-exposed areas in Northeastern Nigeria compared with non-conflict regions.
View Article and Find Full Text PDFSafety and effects of anti-obesity medications on weight loss, cardiometabolic, and psychological outcomes in people living with overweight or obesity: a systematic review and meta-analysis.
EClinicalMedicine
January 2025
National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Background: Overweight and obesity pose serious health challenges for individuals and societies. This study aims to facilitate personalised treatment of obesity by summarising recent research on weight-loss pharmacotherapies, with a focus on their effects on weight reduction, cardiometabolic health, psychological outcomes, and adverse events.
Methods: This systematic review and meta-analysis included searches of Web of Science, PubMed, and Cochrane Central Register of Controlled Trials from inception to June 8, 2024.
Association Between BMI and Neurocognitive Functions Among Middle-aged Obese Adults: Preliminary Findings Using Machine-learning (ML)-based Approach.
Ann Neurosci
January 2025
Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, Delhi, India.
Background: Studies suggest that obesity predisposes individuals to developing cognitive dysfunction and an increased risk of dementia, but the nature of the relationship remains largely unexplored for better prognostic predictors.
Purpose: This study, the first of its kind in Indian participants with obesity, was intended to explore the use of quantification of different neurocognitive indices with increasing body mass index (BMI) among middle-aged participants with obesity. Additionally, machine-learning models were used to analyse the predictive performance of BMI for different cognitive functions.
A comprehensive review of probiotics and human health-current prospective and applications.
Front Microbiol
January 2025
Department of Technologies for Organic Synthesis, Institute of Chemical Technology, Ural Federal University named after the First President of Russia B. N. Yeltsin, Yekaterinburg, Russia.
The beneficial properties of probiotics have always been a point of interest. Probiotics play a major role in maintaining the health of Gastrointestinal Tract (GIT), a healthy digestive system is responsible for modulating all other functions of the body. The effectiveness of probiotics can be enhanced by formulating them with prebiotics the formulation thus formed is referred to as synbiotics.
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