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Hybrid Nanofibrous Membrane with Durable Electret for Anti-Wetting Air Filtration.
Macromol Rapid Commun
January 2025
Innovation Center for Textile Science and Technology, College of Textiles, Donghua University, Shanghai, 201620, China.
Electrospun fibrous materials with fine fibers and small pores are fundamental for particulate matter (PM) filtration, addressing its harmful environmental and health impacts. However, the existing electrospun fibers are still limited to their sub-micron diameters and unstable surface electrostatic effect, leading to deteriorated filtration performance after prolonged storage or wetting. Herein, the study creates nanofibrous membranes with long-time stable electrostatics by electret-enhanced electrospinning.
View Article and Find Full Text PDFPredicting inflammatory response of biomimetic nanofibre scaffolds for tissue regeneration using machine learning and graph theory.
J Mater Chem B
January 2025
Biomaterials Drug Delivery and Nanotechnology Unit, Centre for Biomedical and Biomaterials Research (CBBR), University of Mauritius, Réduit, Mauritius.
Tissue regeneration after a wound occurs through three main overlapping and interrelated stages namely inflammatory, proliferative, and remodelling phases, respectively. The inflammatory phase is key for successful tissue reconstruction and triggers the proliferative phase. The macrophages in the non-healing wounds remain in the inflammatory loop, but their phenotypes can be changed interactions with nanofibre-based scaffolds mimicking the organisation of the native structural support of healthy tissues.
View Article and Find Full Text PDFConglomerated Imiquimod and Metronidazole Incorporated Biodegradable Nanofibrous Mats for Potential Therapy of Cervical Cancer.
Int J Nanomedicine
January 2025
Department of Mechanical Engineering, Chang Gung University, Taoyuan, 33302, Taiwan.
Background: In clinical practice, imiquimod is used to treat Human Papillomavirus (HPV)-related lesions, such as condyloma and Cervical Intraepithelial Neoplasia (CIN). Metronidazole is the most commonly prescribed antibiotic for bacterial vaginosis. The study developed biodegradable imiquimod- and metronidazole-loaded nanofibrous mats and assessed their effectiveness for the topical treatment of cervical cancer, a type of HPV-related lesion.
View Article and Find Full Text PDFFusidic Acid and Lidocaine-Loaded Electrospun Nanofibers as a Dressing for Accelerated Healing of Infected Wounds.
Int J Nanomedicine
January 2025
Advanced Diagnostics and Therapeutics Institute, Health Sector, King Abdulaziz City for Science and Technology (KACST), Riyadh, 11442, Saudi Arabia.
Introduction: Wound treatment is a significant health burden in any healthcare system, which requires proper management to minimize pain and prevent bacterial infections that can complicate the wound healing process.
Rationale: There is a need to develop innovative therapies to accelerate wound healing cost-effectively. Herein, two polymer-based nanofibrous systems were developed using poly-lactic-co-glycolic-acid (PLGA) and polyvinylpyrrolidone (PVP) loaded with a combination of an antibiotic (Fusidic acid, FA) and a local anesthetic (Lidocaine, LDC) via electrospinning technique for an expedited healing process by preventing bacterial infections while reducing the pain sensation.
Dual-mode natural silk nanofiber aerogel with porous layered structure for highly stabilized radiative cooling and heating.
Int J Biol Macromol
January 2025
School of Chemistry and Materials Science, Hubei Engineering University, Xiaogan 43200, China.
Passive Radiant Cooling and Heating are green and sustainable methods of radiant heat management without consuming additional energy. However, the absorption of sunlight and poor insulation of materials can reduce radiative cooling and also affect radiative heating performance. Herein, we have constructed porous hierarchical dual-mode silk nanofibrous aerogel (SNF) films with high mechanical toughness and stability using silk nanofibers/GO.
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