Metal-organic framework catalysed multicomponent reactions towards the synthesis of Pyrans.

Metal-Organic Frameworks (MOFs) gaining increasing interest in heterogeneous catalysis owing to their advantageous properties such as superior porosity, high surface area, ample catalytic sites. Their properties can be tailored by varying the metal ions or metal clusters (nodes) and organic linkers. Magnetically active nano core-shell MOF composites are also discovered for easy separation and reuse of catalyst. MOF catalysed multicomponent reactions (MCRs) satisfy several green chemistry principles and thus can be considered as a sturdy step towards sustainable chemical synthesis. In this article, synthesis of biologically potent pyran scaffolds through MOF catalysed MCR approaches have been reviewed. Preparation of MOF catalyst, its catalytic performance in pyran synthesis, reusability has been discussed with reaction for each example.