Mediastinal lymphangiomas are rare benign tumors arising from lymphatic system malformations, most commonly seen in pediatric populations. In adults, they are exceedingly rare and present diagnostic challenges due to nonspecific symptoms and imaging overlap with other mediastinal masses. Diagnosis is typically based on imaging, including CT and MRI, with histopathology confirming the diagnosis. Surgical resection is the treatment of choice, especially for symptomatic lesions. A 35-year-old female presented with persistent chest pain for two months. Imaging revealed a multiloculated cystic mass in the anterior mediastinum, which was consistent with a lymphangioma. The patient underwent video-assisted thoracoscopic surgery (VATS) for excision, and histopathology confirmed the diagnosis. Postoperatively, she had an uneventful recovery, and follow-up showed no recurrence at six months. This case emphasizes the importance of considering lymphangioma in the differential diagnosis of mediastinal masses, particularly in patients with persistent chest pain, and highlights the role of imaging and surgical management in achieving favorable outcomes.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733399PMC
http://dx.doi.org/10.7759/cureus.75771DOI Listing

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