Linear digital filters are at the core of image reconstruction and processing for many coherent optical imaging techniques, such as digital holography (DH) or optical coherence tomography (OCT). They can also be efficiently implemented using fast Fourier transform (FFT) with appropriate transfer/filter functions that operate in the frequency domain. However, even with optimal filter design, they suffer from side effects such as sidelobe generation or resolution limitations, e.g., when using windowing for apodization. Here, we propose a novel, to the best of our knowledge, nonlinear (NL) filter and apply it to coherent (complex-valued) data. The NL filter preserves correct phase information, reduces sidelobes, and can be implemented indirectly by linear filters, making it almost as performant as linear filters. We demonstrate the usefulness of these filters in OCT data processing, showing the separation of background from signal, and an alternative to classical windowing that retains the full width at half maximum (FWHM) resolution of a rectangular window function, but with sidelobe suppression comparable to other window functions. Contrary to many alternatives, it even performs well in proximity to scattering structures that are subject to speckle noise. Because of its simplicity and advantages, we expect to see widespread applications of the technique beyond the demonstrated applications.
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http://dx.doi.org/10.1364/OL.539047 | DOI Listing |
In this paper, we propose an integrated method for windowing and matched filtering in the analog domain based on microwave photonic technology, which utilizes dispersion regulation of optical waveguide to achieve the windowing processing of broadband signals in the optical domain and the surface acoustic wave filter (SAWF) to achieve the following matched filtering processing in the radio frequency (RF) domain, thus realizing their integration processing in the analog domain. The proposed method is validated by simulation and experiment, in which the integrated processing of matched filtering and windowing in the analog domain for a linear frequency modulation (LFM) signal with a bandwidth of 1 GHz is carried out and the peak to sidelobe ratio (PSLR) of the output signal is -19.55 dB and the mainlobe width (MLW) broadens to 0.
View Article and Find Full Text PDFLinear digital filters are at the core of image reconstruction and processing for many coherent optical imaging techniques, such as digital holography (DH) or optical coherence tomography (OCT). They can also be efficiently implemented using fast Fourier transform (FFT) with appropriate transfer/filter functions that operate in the frequency domain. However, even with optimal filter design, they suffer from side effects such as sidelobe generation or resolution limitations, e.
View Article and Find Full Text PDFAm J Ophthalmol
January 2025
Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan; Center for Eye Policy and Innovation, University of Michigan, Ann Arbor, Michigan; Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor, Michigan. Electronic address:
Purpose: A previously developed machine-learning approach with Kalman-filtering technology accurately predicted disease trajectory for patients with various glaucoma types and severities using clinical trials data. This study assesses performance of the KF approach with real-world data.
Design: Retrospective cohort study.
Biomed Phys Eng Express
January 2025
Mindanao Radiation Physics Center, MSU-Iligan Institute of Technology, Andres Bonifacio Street Tibanga, Iligan City, Lanao Norte, 9200, PHILIPPINES.
To accurately model and validate the 6 MV Elekta Compactlinear accelerator using the Geant4 Application for Tomographic Emission (GATE). In particular, this study focuses on the precise calibration and validation of critical parameters, including jaw collimator positioning, electron source nominal energy, flattening filter geometry, and electron source spot size, which are often not provided in technical documentation. Methods: Simulation of the Elekta Compact6 MV linear accelerator was performed using the Geant4 Application for Tomographic Emission (GATE) v.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
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